Results 1 - 50 of 241 results
Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd. , Lee H , Lee H , Sun R, Niehrs C ., J Biol Chem. January 1, 2022; 298 (2): 101586.
Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects. , Galgoczi S, Ruzo A, Markopoulos C, Yoney A, Phan-Everson T, Li S, Haremaki T , Metzger JJ, Etoc F, Brivanlou AH ., Development. October 1, 2021; 148 (19):
Pinhead antagonizes Admp to promote notochord formation. , Itoh K, Ossipova O, Sokol SY ., iScience. June 25, 2021; 24 (6): 102520.
Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease. , Walentek P ., Cells Tissues Organs. April 26, 2021; 1-18.
BMP signaling is enhanced intracellularly by FHL3 controlling WNT-dependent spatiotemporal emergence of the neural crest. , Alkobtawi M, Pla P, Monsoro-Burq AH ., Cell Rep. January 1, 2021; 35 (12): 109289.
Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos. , Umair Z, Kumar S , Rafiq K , Kumar V , Reman ZU, Lee SH , Kim S, Lee JY , Lee U, Kim J ., Anim Cells Syst (Seoul). November 27, 2020; 24 (6): 359-370.
Tbx2 mediates dorsal patterning and germ layer suppression through inhibition of BMP/GDF and Activin/Nodal signaling. , Reich S, Kayastha P, Teegala S , Weinstein DC ., BMC Mol Cell Biol. May 28, 2020; 21 (1): 39.
Pinhead signaling regulates mesoderm heterogeneity via the FGF receptor-dependent pathway. , Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY ., Development. January 1, 2020; 147 (17):
Foxd4l1.1 negatively regulates transcription of neural repressor ventx1.1 during neuroectoderm formation in Xenopus embryos. , Kumar S , Kumar S , Umair Z, Kumar V , Kumar S , Lee U, Kim J ., Sci Rep. January 1, 2020; 10 (1): 16780.
R-spondins are BMP receptor antagonists in Xenopus early embryonic development. , Lee H , Lee H , Seidl C, Sun R, Glinka A , Niehrs C ., Nat Commun. January 1, 2020; 11 (1): 5570.
Pinhead signaling regulates mesoderm heterogeneity via FGF receptor-dependent pathway. , Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY ., Development. January 1, 2020;
The Spatiotemporal Control of Zygotic Genome Activation. , Gentsch GE , Owens NDL, Smith JC ., iScience. June 28, 2019; 16 485-498.
Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals. , Gentsch GE , Spruce T, Owens NDL, Smith JC ., Nat Commun. January 1, 2019; 10 (1): 4269.
Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling. , Wu KZL, Jones RA, Tachie-Menson T, Macartney TJ, Wood NT, Varghese J, Gourlay R, Soares RF, Smith JC , Sapkota GP., Wellcome Open Res. January 1, 2019; 4 133.
Role of dipeptidyl peptidase-4 as a potentiator of activin/nodal signaling pathway. , Park DS, Kim K, Jang M, Choi SC., BMB Rep. December 1, 2018; 51 (12): 636-641.
Coordinated regulation of the dorsal- ventral and anterior- posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14. , Takebayashi-Suzuki K, Konishi H, Miyamoto T , Nagata T, Uchida M, Suzuki A , Suzuki A ., Dev Growth Differ. April 1, 2018; 60 (3): 158-173.
Fibronectin type III and intracellular domains of Toll-like receptor 4 interactor with leucine-rich repeats (Tril) are required for developmental signaling. , Kim HS , McKnite A, Xie Y, Christian JL ., Mol Biol Cell. January 1, 2018; 29 (5): 523-531.
PAWS1 controls Wnt signalling through association with casein kinase 1α. , Bozatzi P, Dingwell KS, Wu KZ, Cooper F, Cummins TD, Hutchinson LD, Vogt J, Wood NT, Macartney TJ, Varghese J, Gourlay R, Campbell DG, Smith JC , Sapkota GP., EMBO Rep. January 1, 2018; 19 (4):
Pitx1 regulates cement gland development in Xenopus laevis through activation of transcriptional targets and inhibition of BMP signaling. , Jin Y, Weinstein DC ., Dev Biol. January 1, 2018; 437 (1): 41-49.
Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus. , Watanabe T, Yamamoto T , Tsukano K, Hirano S, Horikawa A, Michiue T ., Development. January 1, 2018; 145 (20):
MicroRNA-31 is required for astrocyte specification. , Meares GP, Rajbhandari R, Gerigk M, Tien CL, Chang C , Fehling SC, Rowse A, Mulhern KC, Nair S, Gray GK, Berbari NF, Bredel M, Benveniste EN, Nozell SE., Glia. January 1, 2018; 66 (5): 987-998.
Nodal/Activin Pathway is a Conserved Neural Induction Signal in Chordates. , Le Petillon Y, Luxardi G , Scerbo P , Cibois M, Leon A, Subirana L, Irimia M, Kodjabachian L , Escriva H, Bertrand S., Nat Ecol Evol. August 1, 2017; 1 (8): 1192-1200.
Tbx2 regulates anterior neural specification by repressing FGF signaling pathway. , Cho GS, Park DS, Choi SC, Han JK ., Dev Biol. January 15, 2017; 421 (2): 183-193.
Genomic integration of Wnt/ β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs. , Stevens ML , Chaturvedi P , Rankin SA , Rankin SA , Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM ., Development. January 1, 2017; 144 (7): 1283-1295.
A gene regulatory program controlling early Xenopus mesendoderm formation: Network conservation and motifs. , Charney RM , Paraiso KD , Blitz IL , Cho KWY., Semin Cell Dev Biol. January 1, 2017; 66 12-24.
Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage. , Kirmizitas A, Meiklejohn S, Ciau-Uitz A , Stephenson R , Patient R ., Proc Natl Acad Sci U S A. January 1, 2017; 114 (23): 5814-5821.
Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells. , Zhang Z , Lei A, Xu L, Chen L, Chen Y , Chen Y , Zhang X, Gao Y, Yang X, Zhang M, Cao Y , Cao Y ., J Biol Chem. January 1, 2017; 292 (31): 12842-12859.
Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates. , Marchak A, Grant PA , Neilson KM , Datta Majumdar H, Yaklichkin S , Johnson D, Moody SA ., Dev Biol. January 1, 2017; 429 (1): 213-224.
High-efficiency non-mosaic CRISPR-mediated knock-in and indel mutation in F0 Xenopus. , Aslan Y, Tadjuidje E , Zorn AM , Cha SW ., Development. January 1, 2017; 144 (15): 2852-2858.
ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus. , Ma P, Ren B, Yang X, Sun B, Liu X, Kong Q, Li C, Mao B ., Open Biol. January 1, 2017; 7 (8):
Distinct cis-acting regions control six6 expression during eye field and optic cup stages of eye formation. , Ledford KL, Martinez-De Luna RI , Theisen MA, Rawlins KD, Viczian AS , Zuber ME ., Dev Biol. January 1, 2017; 426 (2): 418-428.
Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis. , Eroshkin FM, Nesterenko AM, Borodulin AV , Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG ., Sci Rep. September 28, 2016; 6 23049.
Syndecan4 coordinates Wnt/JNK and BMP signaling to regulate foregut progenitor development. , Zhang Z , Zhang Z , Rankin SA , Rankin SA , Zorn AM ., Dev Biol. August 1, 2016; 416 (1): 187-199.
Sf3b4-depleted Xenopus embryos: A model to study the pathogenesis of craniofacial defects in Nager syndrome. , Devotta A, Juraver-Geslin H , Gonzalez JA, Hong CS , Saint-Jeannet JP ., Dev Biol. July 15, 2016; 415 (2): 371-382.
Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development. , Schille C, Heller J, Schambony A ., BMC Dev Biol. January 19, 2016; 16 1.
Monitoring Smad Activity In Vivo Using the Xenopus Model System. , Montagner M, Martello G , Piccolo S ., Methods Mol Biol. January 1, 2016; 1344 245-59.
Identification of microRNAs and microRNA targets in Xenopus gastrulae: The role of miR-26 in the regulation of Smad1. , Liu C, Lou CH, Shah V , Ritter R, Talley J, Soibam B, Benham A, Zhu H, Perez E, Shieh YE, Gunaratne PH, Sater AK ., Dev Biol. January 1, 2016; 409 (1): 26-38.
A Retinoic Acid- Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification. , Rankin SA , Rankin SA , Han L , McCracken KW, Kenny AP , Anglin CT, Grigg EA, Crawford CM, Wells JM , Shannon JM, Zorn AM ., Cell Rep. January 1, 2016; 16 (1): 66-78.
Tril targets Smad7 for degradation to allow hematopoietic specification in Xenopus embryos. , Green YS , Kwon S, Mimoto MS, Xie Y, Christian JL ., Development. January 1, 2016; 143 (21): 4016-4026.
Ror2 signaling is required for local upregulation of GDF6 and activation of BMP signaling at the neural plate border. , Schille C, Bayerlová M, Bleckmann A, Schambony A ., Development. January 1, 2016; 143 (17): 3182-94.
The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling. , Wang C , Kam RK , Shi W, Xia Y, Chen X, Cao Y , Sun J, Du Y, Lu G, Chen Z, Chan WY, Chan SO, Deng Y, Zhao H ., J Biol Chem. September 4, 2015; 290 (36): 21925-38.
Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of Receptor-regulated Smads (R-Smads) to Ensure Transforming Growth Factor β (TGFβ)-mediated Germ Layer Induction in Xenopus Embryos. , Sun G , Hu Z, Min Z, Yan X, Guan Z, Su H, Fu Y, Ma X , Chen YG , Zhang MQ, Tao Q , Wu W., J Biol Chem. July 10, 2015; 290 (28): 17239-49.
BMP signalling controls the construction of vertebrate mucociliary epithelia. , Cibois M, Luxardi G , Chevalier B, Thomé V, Mercey O, Zaragosi LE , Barbry P, Pasini A, Marcet B, Kodjabachian L ., Development. July 1, 2015; 142 (13): 2352-63.
Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model. , Pfirrmann T , Emmerich D, Ruokonen P, Quandt D, Buchen R, Fischer-Zirnsak B, Hecht J, Krawitz P, Meyer P, Klopocki E, Stricker S , Lausch E, Seliger B, Hollemann T , Reinhard T, Auw-Haedrich C, Zabel B, Hoffmann K, Villavicencio-Lorini P., Hum Mol Genet. June 1, 2015; 24 (11): 3119-32.
Efficient retina formation requires suppression of both Activin and BMP signaling pathways in pluripotent cells. , Wong KA, Trembley M, Abd Wahab S, Viczian AS ., Biol Open. March 6, 2015; 4 (4): 573-83.
A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy. , Raymond A, Liu B, Liang H, Wei C, Guindani M, Lu Y, Liang S, St John LS, Molldrem J, Nagarajan L., Oncotarget. December 30, 2014; 5 (24): 12675-93.
PV.1 induced by FGF- Xbra functions as a repressor of neurogenesis in Xenopus embryos. , Yoon J, Kim JH , Lee SY , Kim S, Park JB, Lee JY , Kim J ., BMB Rep. December 1, 2014; 47 (12): 673-8.
Genome-wide view of TGFβ/ Foxh1 regulation of the early mesendoderm program. , Chiu WT , Charney Le R, Blitz IL , Fish MB, Li Y , Biesinger J, Xie X, Cho KW ., Development. December 1, 2014; 141 (23): 4537-47.
Fezf2 promotes neuronal differentiation through localised activation of Wnt/ β-catenin signalling during forebrain development. , Zhang S , Li J , Lea R, Vleminckx K , Vleminckx K , Amaya E ., Development. December 1, 2014; 141 (24): 4794-805.
Sox5 Is a DNA-binding cofactor for BMP R-Smads that directs target specificity during patterning of the early ectoderm. , Nordin K, LaBonne C ., Dev Cell. November 10, 2014; 31 (3): 374-382.