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Summary Expression Phenotypes Gene Literature (61) GO Terms (32) Nucleotides (185) Proteins (52) Interactants (499) Wiki
XB--486816

Papers associated with irx1



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The sulfotransferase XB5850668.L is required to apportion embryonic ectodermal domains., Marchak A, Neilson KM, Majumdar HD, Yamauchi K, Klein SL, Moody SA., Dev Dyn. December 1, 2023; 252 (12): 1407-1427.                  


Using Xenopus to discover new candidate genes involved in BOR and other congenital hearing loss syndromes., Neal SJ, Rajasekaran A, Jusić N, Taylor L, Read M, Alfandari D, Alfandari D, Pignoni F, Moody SA., J Exp Zool B Mol Dev Evol. October 13, 2023;             


Zmym4 is required for early cranial gene expression and craniofacial cartilage formation., Jourdeuil K, Neilson KM, Cousin H, Tavares ALP, Majumdar HD, Alfandari D, Alfandari D, Moody SA., Front Cell Dev Biol. January 1, 2023; 11 1274788.          


Hnf1b renal expression directed by a distal enhancer responsive to Pax8., Goea L, Buisson I, Bello V, Eschstruth A, Paces-Fessy M, Le Bouffant R, Chesneau A, Cereghini S, Riou JF, Umbhauer M., Sci Rep. November 19, 2022; 12 (1): 19921.            


Multi-omics approach dissects cis-regulatory mechanisms underlying North Carolina macular dystrophy, a retinal enhanceropathy., Van de Sompele S, Small KW, Cicekdal MB, Soriano VL, D'haene E, Shaya FS, Agemy S, Van der Snickt T, Rey AD, Rosseel T, Van Heetvelde M, Vergult S, Balikova I, Bergen AA, Boon CJF, De Zaeytijd J, Inglehearn CF, Kousal B, Leroy BP, Rivolta C, Vaclavik V, van den Ende J, van Schooneveld MJ, Gómez-Skarmeta JL, Tena JJ, Martinez-Morales JR, Liskova P, Vleminckx K, Vleminckx K, De Baere E., Am J Hum Genet. November 3, 2022; 109 (11): 2029-2048.                                    


Generation of a new six1-null line in Xenopus tropicalis for study of development and congenital disease., Coppenrath K, Tavares ALP, Shaidani NI, Wlizla M, Moody SA, Horb M., Genesis. December 1, 2021; 59 (12): e23453.        


The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos., Massé K, Bhamra S, Paroissin C, Maneta-Peyret L, Boué-Grabot E, Jones EA., Commun Biol. October 7, 2021; 4 (1): 1158.                                


Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., Bright AR, van Genesen S, Li Q, Grasso A, Frölich S, van der Sande M, van Heeringen SJ, Veenstra GJC., EMBO J. May 3, 2021; 40 (9): e104913.                        


Mcrs1 interacts with Six1 to influence early craniofacial and otic development., Neilson KM, Keer S, Bousquet N, Macrorie O, Majumdar HD, Kenyon KL, Alfandari D, Alfandari D, Moody SA., Dev Biol. November 1, 2020; 467 (1-2): 39-50.                  


Six1 proteins with human branchio-oto-renal mutations differentially affect cranial gene expression and otic development., Shah AM, Krohn P, Baxi AB, Tavares ALP, Sullivan CH, Chillakuru YR, Majumdar HD, Neilson KM, Moody SA., Dis Model Mech. March 3, 2020; 13 (3):                                               


Six1 and Irx1 have reciprocal interactions during cranial placode and otic vesicle formation., Sullivan CH, Majumdar HD, Neilson KM, Moody SA., Dev Biol. February 1, 2019; 446 (1): 68-79.                      


The neural border: Induction, specification and maturation of the territory that generates neural crest cells., Pla P, Monsoro-Burq AH., Dev Biol. December 1, 2018; 444 Suppl 1 S36-S46.    


Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates., Marchak A, Grant PA, Neilson KM, Datta Majumdar H, Yaklichkin S, Johnson D, Moody SA., Dev Biol. September 1, 2017; 429 (1): 213-224.                    


Translational profiling of retinal ganglion cell optic nerve regeneration in Xenopus laevis., Whitworth GB, Misaghi BC, Rosenthal DM, Mills EA, Heinen DJ, Watson AH, Ives CW, Ali SH, Bezold K, Marsh-Armstrong N, Watson FL., Dev Biol. June 15, 2017; 426 (2): 360-373.              


Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        


Gene expression analysis of developing cell groups in the pretectal region of Xenopus laevis., Morona R, Ferran JL, Puelles L, González A., J Comp Neurol. March 1, 2017; 525 (4): 715-752.                                            


Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development., Neilson KM, Abbruzzesse G, Kenyon K, Bartolo V, Krohn P, Alfandari D, Alfandari D, Moody SA., Dev Biol. January 15, 2017; 421 (2): 171-182.                    


An Evolutionarily Conserved Network Mediates Development of the zona limitans intrathalamica, a Sonic Hedgehog-Secreting Caudal Forebrain Signaling Center., Sena E, Feistel K, Durand BC., J Dev Biol. October 20, 2016; 4 (4):       


Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm., Gaur S, Mandelbaum M, Herold M, Majumdar HD, Neilson KM, Maynard TM, Mood K, Daar IO, Moody SA., Genesis. June 1, 2016; 54 (6): 334-49.                          


Evidence for an amphibian sixth digit., Hayashi S, Kobayashi T, Yano T, Kamiyama N, Egawa S, Seki R, Takizawa K, Okabe M, Yokoyama H, Tamura K., Zoological Lett. June 15, 2015; 1 17.                  


Prepatterning and patterning of the thalamus along embryonic development of Xenopus laevis., Bandín S, Morona R, González A., Front Neuroanat. February 3, 2015; 9 107.                                                    


The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog., Juraver-Geslin HA, Gómez-Skarmeta JL, Durand BC., Dev Biol. December 1, 2014; 396 (1): 107-20.                    


Setting appropriate boundaries: fate, patterning and competence at the neural plate border., Groves AK, LaBonne C., Dev Biol. May 1, 2014; 389 (1): 2-12.    


Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers., Plouhinec JL, Roche DD, Pegoraro C, Figueiredo AL, Maczkowiak F, Brunet LJ, Milet C, Vert JP, Pollet N, Harland RM, Monsoro-Burq AH., Dev Biol. February 15, 2014; 386 (2): 461-72.                                            


Conserved structural domains in FoxD4L1, a neural forkhead box transcription factor, are required to repress or activate target genes., Klein SL, Neilson KM, Orban J, Yaklichkin S, Hoffbauer J, Mood K, Daar IO, Moody SA., PLoS One. April 4, 2013; 8 (4): e61845.                  


HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2., Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyryläinen R, Shan J, Vainio S, Umbhauer M, Cereghini S., Development. February 1, 2013; 140 (4): 873-85.  


Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene., Nicetto D, Hahn M, Jung J, Schneider TD, Straub T, David R, Schotta G, Rupp RA., PLoS Genet. January 1, 2013; 9 (1): e1003188.                                                                


Specific domains of FoxD4/5 activate and repress neural transcription factor genes to control the progression of immature neural ectoderm to differentiating neural plate., Neilson KM, Klein SL, Mhaske P, Mood K, Daar IO, Moody SA., Dev Biol. May 15, 2012; 365 (2): 363-75.                        


Over-expression of atf4 in Xenopus embryos interferes with neurogenesis and eye formation., Liu JT, Yang Y, Guo XG, Chen M, Ding HZ, Chen YL, Chen YL, Wang MR., Dongwuxue Yanjiu. October 1, 2011; 32 (5): 485-91.            


A conserved function of the chromatin ATPase Kismet in the regulation of hedgehog expression., Terriente-Félix A, Molnar C, Gómez-Skarmeta JL, de Celis JF., Dev Biol. February 15, 2011; 350 (2): 382-92.                  


An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation., Tena JJ, Alonso ME, de la Calle-Mustienes E, Splinter E, de Laat W, Manzanares M, Gómez-Skarmeta JL., Nat Commun. January 1, 2011; 2 310.    


Smicl is required for phosphorylation of RNA polymerase II and affects 3'-end processing of RNA at the midblastula transition in Xenopus., Collart C, Ramis JM, Down TA, Smith JC., Development. October 1, 2009; 136 (20): 3451-61.


The role of the visceral mesoderm in the development of the gastrointestinal tract., McLin VA, Henning SJ, Jamrich M., Gastroenterology. June 1, 2009; 136 (7): 2074-91.


The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx., Rodríguez-Seguel E, Alarcón P, Gómez-Skarmeta JL., Dev Biol. May 15, 2009; 329 (2): 258-68.                


foxD5 plays a critical upstream role in regulating neural ectodermal fate and the onset of neural differentiation., Yan B, Neilson KM, Moody SA., Dev Biol. May 1, 2009; 329 (1): 80-95.              


A dual requirement for Iroquois genes during Xenopus kidney development., Alarcón P, Rodríguez-Seguel E, Fernández-González A, Rubio R, Gómez-Skarmeta JL., Development. October 1, 2008; 135 (19): 3197-207.                            


The prepattern transcription factor Irx3 directs nephron segment identity., Reggiani L, Raciti D, Airik R, Kispert A, Brändli AW., Genes Dev. September 15, 2007; 21 (18): 2358-70.                


The competence of Xenopus blastomeres to produce neural and retinal progeny is repressed by two endo-mesoderm promoting pathways., Yan B, Moody SA., Dev Biol. May 1, 2007; 305 (1): 103-19.        


Identification and developmental expression analysis of a novel homeobox gene closely linked to the mouse Twirler mutation., Liu H, Liu W, Maltby KM, Lan Y, Jiang R., Gene Expr Patterns. August 1, 2006; 6 (6): 632-6.


Induction of the neural crest and the opportunities of life on the edge., Huang X, Saint-Jeannet JP., Dev Biol. November 1, 2004; 275 (1): 1-11.


Xenopus paraxis homologue shows novel domains of expression., Carpio R, Honoré SM, Araya C, Mayor R., Dev Dyn. November 1, 2004; 231 (3): 609-13.        


Role of BMP signaling and the homeoprotein Iroquois in the specification of the cranial placodal field., Glavic A, Maris Honoré S, Gloria Feijóo C, Bastidas F, Allende ML, Mayor R., Dev Biol. August 1, 2004; 272 (1): 89-103.


Molecular anatomy of placode development in Xenopus laevis., Schlosser G, Ahrens K., Dev Biol. July 15, 2004; 271 (2): 439-66.                          


Interplay between Notch signaling and the homeoprotein Xiro1 is required for neural crest induction in Xenopus embryos., Glavic A, Silva F, Aybar MJ, Bastidas F, Mayor R., Development. January 1, 2004; 131 (2): 347-59.              


Xenopus Xlmo4 is a GATA cofactor during ventral mesoderm formation and regulates Ldb1 availability at the dorsal mesoderm and the neural plate., de la Calle-Mustienes E, Lu Z, Cortés M, Andersen B, Modolell J, Gómez-Skarmeta JL., Dev Biol. December 15, 2003; 264 (2): 564-81.


Xiro homeoproteins coordinate cell cycle exit and primary neuron formation by upregulating neuronal-fate repressors and downregulating the cell-cycle inhibitor XGadd45-gamma., de la Calle-Mustienes E, Glavic A, Modolell J, Gómez-Skarmeta JL., Mech Dev. November 1, 2002; 119 (1): 69-80.              


Molecular cloning and characterization of dullard: a novel gene required for neural development., Satow R, Chan TC, Asashima M., Biochem Biophys Res Commun. July 5, 2002; 295 (1): 85-91.                  


The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation., Glavic A, Gómez-Skarmeta JL, Mayor R., Development. April 1, 2002; 129 (7): 1609-21.                  


The Xiro-repressed gene CoREST is expressed in Xenopus neural territories., de la Calle-Mustienes E, Modolell J, Gómez-Skarmeta JL., Mech Dev. January 1, 2002; 110 (1-2): 209-11.  


Xiro-1 controls mesoderm patterning by repressing bmp-4 expression in the Spemann organizer., Glavic A, Gómez-Skarmeta JL, Mayor R., Dev Dyn. November 1, 2001; 222 (3): 368-76.      

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