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Summary Expression Phenotypes Gene Literature (192) GO Terms (6) Nucleotides (126) Proteins (56) Interactants (656) Wiki
XB--487965

Papers associated with nkx2-5



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Early life exposure to perfluorooctanesulfonate (PFOS) impacts vital biological processes in Xenopus laevis: Integrated morphometric and transcriptomic analyses., Ismail T, Lee HK, Lee H, Kim Y, Kim E, Lee JY, Kim KB, Ryu HY, Cho DH, Kwon TK, Park TJ, Kwon T, Lee HS, Lee HS., Ecotoxicol Environ Saf. January 1, 2024; 269 115820.                      

Normal Table of Xenopus development: a new graphical resource., Zahn N, James-Zorn C, Ponferrada VG, Adams DS, Grzymkowski J, Buchholz DR, Nascone-Yoder NM, Horb M, Moody SA, Vize PD, Zorn AM., Development. July 15, 2022; 149 (14):                         

Impact of glyphosate-based herbicide on early embryonic development of the amphibian Xenopus laevis., Flach H, Lenz A, Pfeffer S, Kühl M, Kühl SJ., Aquat Toxicol. March 1, 2022; 244 106081.

Identification of ZBTB26 as a Novel Risk Factor for Congenital Hypothyroidism., Vick P, Eberle B, Choukair D, Weiss B, Roeth R, Schneider I, Paramasivam N, Bettendorf M, Rappold GA., Genes (Basel). November 24, 2021; 12 (12):                     

Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease., Getwan M, Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):                                                   

A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis., Pokrovsky D, Forné I, Straub T, Imhof A, Rupp RAW., PLoS Biol. September 1, 2021; 19 (9): e3001377.                        

Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway., Wang H, Wang C, Wang C, Wang C, Long Q, Zhang Y, Wang M, Liu J, Qi X, Cai D, Lu G, Sun J, Yao YG, Chan WY, Chan WY, Deng Y, Zhao H., Development. May 15, 2021; 148 (10):                                           

Transcriptional regulatory elements of hif1α in a distal locus of islet1 in Xenopus laevis., Miyakawa M, Katada T, Numa Y, Kinoshita T., Comp Biochem Physiol B Biochem Mol Biol. January 1, 2021; 255 110598.

Amphibian thalamic nuclear organization during larval development and in the adult frog Xenopus laevis: Genoarchitecture and hodological analysis., Morona R, Bandín S, López JM, Moreno N, González A., J Comp Neurol. October 1, 2020; 528 (14): 2361-2403.                                                                

Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism., Choukair D, Eberle B, Vick P, Hermanns P, Weiss B, Paramasivam N, Schlesner M, Lornsen K, Roeth R, Klutmann C, Kreis J, Hoffmann GF, Pohlenz J, Rappold GA, Bettendorf M., Horm Res Paediatr. January 1, 2020; 93 (1): 16-29.

Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation., Nasr T, Mancini P, Rankin SA, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, Trisno SL, Cha SW, Wells JM, Kofron MJ, Zorn AM., Dev Cell. December 16, 2019; 51 (6): 665-674.e6.                  

Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis., Schwenty-Lara J, Nürnberger A, Borchers A., Dev Dyn. June 1, 2019; 248 (6): 465-476.                  

The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis., Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M., Dev Biol. May 1, 2019; 449 (1): 1-13.                                  

RPSA, a candidate gene for isolated congenital asplenia, is required for pre-rRNA processing and spleen formation in Xenopus., Griffin JN, Sondalle SB, Robson A, Mis EK, Griffin G, Kulkarni SS, Deniz E, Baserga SJ, Khokha MK., Development. October 18, 2018; 145 (20):                   

Evaluation of the toxic effects of celecoxib on Xenopus embryo development., Yoon YH, Kim JY, Bae YC, Nam SW, Cho HJ, Lee S, Chung HY, Lee HS, Lee HS, Park MJ., Biochem Biophys Res Commun. June 22, 2018; 501 (2): 329-335.        

Sema3a plays a role in the pathogenesis of CHARGE syndrome., Ufartes R, Schwenty-Lara J, Freese L, Neuhofer C, Möller J, Wehner P, van Ravenswaaij-Arts CMA, Wong MTY, Schanze I, Tzschach A, Bartsch O, Borchers A, Pauli S., Hum Mol Genet. April 15, 2018; 27 (8): 1343-1352.  

Frizzled-7 is required for Xenopus heart development., Abu-Elmagd M, Mulvaney J, Wheeler GN., Biol Open. December 15, 2017; 6 (12): 1861-1868.            

Id genes are essential for early heart formation., Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR., Genes Dev. July 1, 2017; 31 (13): 1325-1338.                

Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis., Pitcairn E, Harris H, Epiney J, Pai VP, Lemire JM, Ye B, Shi NQ, Levin M, McLaughlin KA., Commun Integr Biol. May 10, 2017; 10 (3): e1309488.                            

The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis., Hempel A, Kühl SJ, Rothe M, Rao Tata P, Sirbu IO, Vainio SJ, Kühl M., Dev Biol. April 1, 2017; 424 (1): 28-39.                                  

Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs., Stevens ML, Chaturvedi P, Rankin SA, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM., Development. April 1, 2017; 144 (7): 1283-1295.                            

FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue., Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D., Int J Dev Biol. January 1, 2017; 61 (3-4-5): 293-302.              

The splicing factor SRSF1 modulates pattern formation by inhibiting transcription of tissue specific genes during embryogenesis., Lee SH, Lee HK, Lee HK, Kim C, Kim YK, Ismail T, Jeong Y, Park K, Park JW, Kwon OS, Kang BS, Lee DS, Park MJ, Park DS, Lee HS, Lee HS., Biochem Biophys Res Commun. September 2, 2016; 477 (4): 1011-1016.                

CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart., Blech-Hermoni Y, Sullivan CB, Jenkins MW, Wessely O, Ladd AN., Dev Dyn. August 1, 2016; 245 (8): 854-73.                      

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA, Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM., Cell Rep. June 28, 2016; 16 (1): 66-78.                                              

Early ketamine exposure results in cardiac enlargement and heart dysfunction in Xenopus embryos., Guo R, Liu G, Du M, Shi Y, Shi Y, Jiang P, Liu X, Liu L, Liu J, Xu Y, Xu Y., BMC Anesthesiol. April 18, 2016; 16 23.              

pdzrn3 is required for pronephros morphogenesis in Xenopus laevis., Marracci S, Vangelisti A, Raffa V, Andreazzoli M, Dente L., Int J Dev Biol. January 1, 2016; 60 (1-3): 57-63.                  

Perfluoroheptanoic acid affects amphibian embryogenesis by inducing the phosphorylation of ERK and JNK., Kim M, Park MS, Son J, Park I, Lee HK, Kim C, Min BH, Ryoo J, Choi KS, Lee DS, Lee HS., Int J Mol Med. December 1, 2015; 36 (6): 1693-700.

Characterization of ticlopidine-induced developmental and teratogenic defects in Xenopus embryos and human endothelial cells., Park MS, Kim JW, Park I, Lee HK, Kim C, Jo C, Kim YK, Min BH, Ryoo J, Lee DS, Bae JS, Kim SH, Ye SK, Park MJ, Lee HS., Chem Biol Interact. October 5, 2015; 240 172-8.

Predicting Variabilities in Cardiac Gene Expression with a Boolean Network Incorporating Uncertainty., Grieb M, Burkovski A, Sträng JE, Kraus JM, Groß A, Palm G, Kühl M, Kestler HA., PLoS One. July 16, 2015; 10 (7): e0131832.        

Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity., Dorn T, Goedel A, Lam JT, Haas J, Tian Q, Herrmann F, Bundschu K, Dobreva G, Schiemann M, Dirschinger R, Guo Y, Kühl SJ, Sinnecker D, Lipp P, Laugwitz KL, Kühl M, Moretti A., Stem Cells. April 1, 2015; 33 (4): 1113-29.              

The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    

Nkx2.5 is involved in myeloid cell differentiation at anterior ventral blood islands in the Xenopus embryo., Sakata H, Maéno M., Dev Growth Differ. October 1, 2014; 56 (8): 544-54.              

Diverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis., Rozario T, Mead PE, DeSimone DW., Mech Dev. August 1, 2014; 133 203-17.                

Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells., Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD., Stem Cells. June 1, 2014; 32 (6): 1515-26.              

Comparative analysis reveals distinct and overlapping functions of Mef2c and Mef2d during cardiogenesis in Xenopus laevis., Guo Y, Kühl SJ, Pfister AS, Cizelsky W, Denk S, Beer-Molz L, Kühl M., PLoS One. January 17, 2014; 9 (1): e87294.                

A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development., Paranjpe SS, Jacobi UG, van Heeringen SJ, Veenstra GJ., BMC Genomics. November 6, 2013; 14 762.              

In vivo evaluation and comparison of developmental toxicity and teratogenicity of perfluoroalkyl compounds using Xenopus embryos., Kim M, Son J, Park MS, Ji Y, Chae S, Jun C, Bae JS, Kwon TK, Choo YS, Yoon H, Yoon D, Ryoo J, Kim SH, Park MJ, Lee HS., Chemosphere. October 1, 2013; 93 (6): 1153-60.

Tcf21 regulates the specification and maturation of proepicardial cells., Tandon P, Miteva YV, Kuchenbrod LM, Cristea IM, Conlon FL., Development. June 1, 2013; 140 (11): 2409-21.                                

Developmental origins of a novel gut morphology in frogs., Bloom S, Ledon-Rettig C, Infante C, Everly A, Hanken J, Nascone-Yoder N., Evol Dev. May 1, 2013; 15 (3): 213-23.

Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut., Dush MK, Nascone-Yoder NM., Development. April 1, 2013; 140 (7): 1457-66.                      

Islet1-expressing cardiac progenitor cells: a comparison across species., Pandur P, Sirbu IO, Kühl SJ, Philipp M, Kühl M., Dev Genes Evol. March 1, 2013; 223 (1-2): 117-29.          

Regulation of primitive hematopoiesis by class I histone deacetylases., Shah RR, Koniski A, Shinde M, Blythe SA, Fass DM, Haggarty SJ, Palis J, Klein PS., Dev Dyn. February 1, 2013; 242 (2): 108-21.              

Prolonged FGF signaling is necessary for lung and liver induction in Xenopus., Shifley ET, Kenny AP, Rankin SA, Rankin SA, Zorn AM., BMC Dev Biol. September 18, 2012; 12 27.                      

Dissociation of cardiogenic and postnatal myocardial activities of GATA4., Gallagher JM, Komati H, Roy E, Nemer M, Latinkić BV., Mol Cell Biol. June 1, 2012; 32 (12): 2214-23.

Inhibition of heart formation by lithium is an indirect result of the disruption of tissue organization within the embryo., Martin LK, Bratoeva M, Mezentseva NV, Bernanke JM, Remond MC, Ramsdell AF, Eisenberg CA, Eisenberg LM., Dev Growth Differ. February 1, 2012; 54 (2): 153-66.                

Tbx5 overexpression favors a first heart field lineage in murine embryonic stem cells and in Xenopus laevis embryos., Herrmann F, Bundschu K, Kühl SJ, Kühl M., Dev Dyn. December 1, 2011; 240 (12): 2634-45.  

Canonical WNT signaling enhances stem cell expression in the developing heart without a corresponding inhibition of cardiogenic differentiation., Martin LK, Mezentseva NV, Bratoeva M, Ramsdell AF, Eisenberg CA, Eisenberg LM., Stem Cells Dev. November 1, 2011; 20 (11): 1973-83.

Focal adhesion kinase is essential for cardiac looping and multichamber heart formation., Doherty JT, Conlon FL, Mack CP, Taylor JM., Genesis. August 1, 2010; 48 (8): 492-504.                  

Examining the cardiac NK-2 genes in early heart development., Bartlett H, Veenstra GJ, Weeks DL., Pediatr Cardiol. April 1, 2010; 31 (3): 335-41.

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