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Summary Expression Phenotypes Gene Literature (88) GO Terms (2) Nucleotides (160) Proteins (68) Interactants (1023) Wiki
XB--488221

Papers associated with ptch1



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Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components., Hantel F, Liu H, Fechtner L, Neuhaus H, Ding J, Arlt D, Walentek P, Villavicencio-Lorini P, Gerhardt C, Hollemann T, Pfirrmann T., J Cell Sci. May 1, 2022; 135 (9):                                     

Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development., Sun J, Yoon J, Lee M, Lee HK, Hwang YS, Daar IO., Cell Rep. February 1, 2022; 38 (5): 110312.                                          

Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease., Getwan M, Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):                                                   

DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes., Marquez J, Mann N, Arana K, Deniz E, Ji W, Konstantino M, Mis EK, Deshpande C, Jeffries L, McGlynn J, Hugo H, Widmeier E, Konrad M, Tasic V, Morotti R, Baptista J, Ellard S, Lakhani SA, Hildebrandt F, Khokha MK., J Med Genet. July 1, 2021; 58 (7): 453-464.                        

A temporally resolved transcriptome for developing "Keller" explants of the Xenopus laevis dorsal marginal zone., Kakebeen AD, Huebner RJ, Shindo A, Kwon K, Kwon T, Wills AE, Wallingford JB., Dev Dyn. May 1, 2021; 250 (5): 717-731.              

Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience., Willsey HR, Exner CRT, Xu Y, Xu Y, Everitt A, Sun N, Wang B, Dea J, Schmunk G, Zaltsman Y, Teerikorpi N, Kim A, Anderson AS, Shin D, Seyler M, Nowakowski TJ, Harland RM, Willsey AJ, State MW., Neuron. March 3, 2021; 109 (5): 788-804.e8.

Thyroid hormone-induced expression of Foxl1 in subepithelial fibroblasts correlates with adult stem cell development during Xenopus intestinal remodeling., Hasebe T, Fujimoto K, Ishizuya-Oka A., Sci Rep. November 26, 2020; 10 (1): 20715.                

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

Smoothened stimulation by membrane sterols drives Hedgehog pathway activity., Deshpande I, Liang J, Hedeen D, Roberts KJ, Zhang Y, Ha B, Latorraca NR, Faust B, Dror RO, Beachy PA, Myers BR, Manglik A., Nature. July 1, 2019; 571 (7764): 284-288.

Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway., Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E., Mech Dev. April 1, 2019; 156 20-31.                              

Gli2 is required for the induction and migration of Xenopus laevis neural crest., Cerrizuela S, Vega-López GA, Palacio MB, Tríbulo C, Aybar MJ, Aybar MJ., Mech Dev. December 1, 2018; 154 219-239.                      

The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slices., Dale E, Grunnet M, Pehrson AL, Frederiksen K, Larsen PH, Nielsen J, Stensbøl TB, Ebert B, Yin H, Lu D, Liu H, Jensen TN, Yang CR, Sanchez C., Brain Res. June 15, 2018; 1689 1-11.

Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel., Rokic MB, Castro P, Leiva-Salcedo E, Tomic M, Stojilkovic SS, Coddou C., Int J Mol Sci. April 11, 2018; 19 (4):                     

Divergent axial morphogenesis and early shh expression in vertebrate prospective floor plate., Kremnyov S, Henningfeld K, Viebahn C, Tsikolia N., Evodevo. January 31, 2018; 9 4.                    

Hyperinnervation improves Xenopus laevis limb regeneration., Mitogawa K, Makanae A, Satoh A., Dev Biol. January 15, 2018; 433 (2): 276-286.                    

Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads., Piprek RP, Damulewicz M, Kloc M, Kubiak JZ., Differentiation. January 1, 2018; 100 46-56.                          

Sonic hedgehog antagonists reduce size and alter patterning of the frog inner ear., Zarei S, Zarei K, Fritzsch B, Elliott KL., Dev Neurobiol. December 1, 2017; 77 (12): 1385-1400.                

hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus., Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K., Dev Biol. October 1, 2017; 430 (1): 188-201.                      

Genome-wide identification of thyroid hormone receptor targets in the remodeling intestine during Xenopus tropicalis metamorphosis., Fu L, Das B, Matsuura K, Fujimoto K, Heimeier RA, Shi YB, Shi YB., Sci Rep. July 25, 2017; 7 (1): 6414.            

High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  

Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling., Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J., Development. November 1, 2016; 143 (21): 3944-3955.                        

Genome evolution in the allotetraploid frog Xenopus laevis., Session AM, Uno Y, Kwon T, Chapman JA, Toyoda A, Takahashi S, Fukui A, Hikosaka A, Suzuki A, Kondo M, van Heeringen SJ, Quigley I, Heinz S, Ogino H, Ochi H, Hellsten U, Lyons JB, Simakov O, Putnam N, Stites J, Kuroki Y, Tanaka T, Michiue T, Watanabe M, Bogdanovic O, Lister R, Georgiou G, Paranjpe SS, van Kruijsbergen I, Shu S, Carlson J, Kinoshita T, Ohta Y, Mawaribuchi S, Jenkins J, Grimwood J, Schmutz J, Mitros T, Mozaffari SV, Suzuki Y, Haramoto Y, Yamamoto TS, Takagi C, Heald R, Miller K, Haudenschild C, Kitzman J, Nakayama T, Izutsu Y, Robert J, Fortriede J, Burns K, Lotay V, Karimi K, Yasuoka Y, Dichmann DS, Flajnik MF, Houston DW, Shendure J, DuPasquier L, Vize PD, Zorn AM, Ito M, Marcotte EM, Wallingford JB, Ito Y, Asashima M, Ueno N, Matsuda Y, Veenstra GJ, Fujiyama A, Harland RM, Taira M, Rokhsar DS., Nature. October 20, 2016; 538 (7625): 336-343.                              

Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 during visual system development., Pfirrmann T, Jandt E, Ranft S, Lokapally A, Neuhaus H, Perron M, Hollemann T., Proc Natl Acad Sci U S A. September 6, 2016; 113 (36): 10103-8.                    

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA, Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM., Cell Rep. June 28, 2016; 16 (1): 66-78.                                              

ATP4 and ciliation in the neuroectoderm and endoderm of Xenopus embryos and tadpoles., Walentek P, Hagenlocher C, Beyer T, Müller C, Feistel K, Schweickert A, Harland RM, Blum M., Data Brief. April 20, 2015; 4 22-31.            

Spatiotemporal integration of developmental cues in neural development., Borodinsky LN, Belgacem YH, Swapna I, Visina O, Balashova OA, Sequerra EB, Tu MK, Levin JB, Spencer KA, Castro PA, Hamilton AM, Shim S., Dev Neurobiol. April 1, 2015; 75 (4): 349-59.    

Inversion of Sonic hedgehog action on its canonical pathway by electrical activity., Belgacem YH, Borodinsky LN., Proc Natl Acad Sci U S A. March 31, 2015; 112 (13): 4140-5.                              

The medaka dhc2 mutant reveals conserved and distinct mechanisms of Hedgehog signaling in teleosts., Yamamoto T, Tsukahara T, Ishiguro T, Hagiwara H, Taira M, Takeda H., BMC Dev Biol. February 3, 2015; 15 9.

Early development of the neural plate: new roles for apoptosis and for one of its main effectors caspase-3., Juraver-Geslin HA, Durand BC., Genesis. February 1, 2015; 53 (2): 203-24.          

[The Cytoskelrtal Protein Zvxin Interacts with the Hedgehog Receptor Patched]., Martynova NU, Ermolina LV, Eroshkin FM, Zarayskiy AG., Bioorg Khim. January 1, 2015; 41 (6): 744-8.

Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression., Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW., Dev Biol. November 15, 2014; 395 (2): 287-98.                    

The chicken left right organizer has nonmotile cilia which are lost in a stage-dependent manner in the talpid(3) ciliopathy., Stephen LA, Johnson EJ, Davis GM, McTeir L, Pinkham J, Jaberi N, Davey MG., Genesis. June 1, 2014; 52 (6): 600-13.            

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling., Niewiadomski P, Kong JH, Ahrends R, Ma Y, Humke EW, Khan S, Teruel MN, Novitch BG, Rohatgi R., Cell Rep. January 16, 2014; 6 (1): 168-81.

Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling., Schwend T, Jin Z, Jiang K, Mitchell BJ, Jia J, Yang J., J Biol Chem. November 8, 2013; 288 (45): 32809-32820.                

Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specification., Leung A, Ciau-Uitz A, Pinheiro P, Monteiro R, Zuo J, Vyas P, Patient R, Porcher C., Dev Cell. January 28, 2013; 24 (2): 144-58.                                

Characterization of heterologously expressed transporter genes by patch- and voltage-clamp methods: application to cyclic nucleotide-dependent responses., Lemtiri-Chlieh F, Ali R., Methods Mol Biol. January 1, 2013; 1016 67-93.

Hes4 controls proliferative properties of neural stem cells during retinal ontogenesis., El Yakoubi W, Borday C, Hamdache J, Parain K, Tran HT, Vleminckx K, Vleminckx K, Perron M, Locker M., Stem Cells. December 1, 2012; 30 (12): 2784-95.              

The Hedgehog receptor patched functions in multidrug transport and chemotherapy resistance., Bidet M, Tomico A, Martin P, Guizouarn H, Mollat P, Mus-Veteau I., Mol Cancer Res. November 1, 2012; 10 (11): 1496-508.

Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation., Borday C, Cabochette P, Parain K, Mazurier N, Janssens S, Tran HT, Sekkali B, Bronchain O, Vleminckx K, Vleminckx K, Locker M, Perron M., Development. October 1, 2012; 139 (19): 3499-509.                    

Indian hedgehog signaling is required for proper formation, maintenance and migration of Xenopus neural crest., Agüero TH, Fernández JP, López GA, Tríbulo C, Aybar MJ., Dev Biol. April 15, 2012; 364 (2): 99-113.                    

Thyroid hormone-induced sonic hedgehog signal up-regulates its own pathway in a paracrine manner in the Xenopus laevis intestine during metamorphosis., Hasebe T, Kajita M, Fu L, Shi YB, Ishizuya-Oka A., Dev Dyn. February 1, 2012; 241 (2): 403-14.        

Functional clustering drives encoding improvement in a developing brain network during awake visual learning., Podgorski K, Dunfield D, Haas K., PLoS Biol. January 1, 2012; 10 (1): e1001236.                  

ZFP932 suppresses cellular Hedgehog response and Patched1 transcription., Huang GJ, He Z, Ma L., Vitam Horm. January 1, 2012; 88 309-32.

The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo., Min TH, Kriebel M, Hou S, Pera EM., Dev Biol. October 1, 2011; 358 (1): 262-76.                            

Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung., Lazrak A, Jurkuvenaite A, Chen L, Keeling KM, Collawn JF, Bedwell DM, Matalon S., Am J Physiol Lung Cell Mol Physiol. October 1, 2011; 301 (4): L557-67.

Hedgehog signaling regulates size of the dorsal aortae and density of the plexus during avian vascular development., Moran CM, Salanga MC, Krieg PA., Dev Dyn. June 1, 2011; 240 (6): 1354-64.            

MIM regulates vertebrate neural tube closure., Liu W, Komiya Y, Mezzacappa C, Khadka DK, Runnels L, Habas R., Development. May 1, 2011; 138 (10): 2035-47.                            

A revised model of Xenopus dorsal midline development: differential and separable requirements for Notch and Shh signaling., Peyrot SM, Wallingford JB, Harland RM., Dev Biol. April 15, 2011; 352 (2): 254-66.                              

Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord., Belgacem YH, Borodinsky LN., Proc Natl Acad Sci U S A. March 15, 2011; 108 (11): 4482-7.        

A novel KRAB domain-containing zinc finger transcription factor ZNF431 directly represses Patched1 transcription., He Z, Cai J, Lim JW, Kroll K, Ma L., J Biol Chem. March 4, 2011; 286 (9): 7279-89.  

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