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Summary Expression Phenotypes Gene Literature (86) GO Terms (2) Nucleotides (498) Proteins (83) Interactants (442) Wiki
XB--6046301

Papers associated with tpm3



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Structure of a eukaryotic cholinephosphotransferase-1 reveals mechanisms of substrate recognition and catalysis., Wang L, Zhou M., Nat Commun. May 13, 2023; 14 (1): 2753.


Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos., Lo Furno E, Busseau I, Aze A, Lorenzi C, Saghira C, Danzi MC, Zuchner S, Maiorano D., Nucleic Acids Res. January 25, 2022; 50 (2): 885-898.                          


Physical basis for distinct basal and mechanically gated activity of the human K+ channel TRAAK., Rietmeijer RA, Sorum B, Li B, Brohawn SG., Neuron. September 15, 2021; 109 (18): 2902-2913.e4.            


Mechanistic insights into volatile anesthetic modulation of K2P channels., Wague A, Joseph TT, Woll KA, Bu W, Vaidya KA, Bhanu NV, Garcia BA, Nimigean CM, Eckenhoff RG, Riegelhaupt PM., Elife. December 21, 2020; 9                   


Predation threats for a 24-h period activated the extension of axons in the brains of Xenopus tadpoles., Mori T, Kitani Y, Hatakeyama D, Machida K, Goto-Inoue N, Hayakawa S, Yamamoto N, Kashiwagi K, Kashiwagi A., Sci Rep. July 16, 2020; 10 (1): 11737.                    


Effects of intersubunit amino acid substitutions on GABA receptor sensitivity to the ectoparasiticide fluralaner., Yamato K, Nakata Y, Takashima M, Ozoe F, Asahi M, Kobayashi M, Ozoe Y., Pestic Biochem Physiol. February 1, 2020; 163 123-129.


Identifying Common Features in the Activation of Melanocortin-2 Receptors: Studies on the Xenopus tropicalis Melanocortin-2 Receptor., Davis PE, Wilkinson EC, Dores RM., Int J Mol Sci. August 26, 2019; 20 (17):           


Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine., Ramírez D, Bedoya M, Kiper AK, Rinné S, Morales-Navarro S, Hernández-Rodríguez EW, Sepúlveda FV, Decher N, González W., Int J Mol Sci. May 7, 2019; 20 (9):             


Multiple functional neurosteroid binding sites on GABAA receptors., Chen ZW, Bracamontes JR, Budelier MM, Germann AL, Shin DJ, Kathiresan K, Qian MX, Manion B, Cheng WWL, Reichert DE, Akk G, Covey DF, Evers AS., PLoS Biol. March 7, 2019; 17 (3): e3000157.            


Transmembrane Helices 2 and 3 Determine the Localization of Plasma Membrane Intrinsic Proteins in Eukaryotic Cells., Wang H, Zhang L, Tao Y, Wang Z, Shen D, Dong H., Front Plant Sci. January 1, 2019; 10 1671.                                      


Nicotine-sensitive acetylcholine receptors are relevant pharmacological targets for the control of multidrug resistant parasitic nematodes., Charvet CL, Guégnard F, Courtot E, Cortet J, Neveu C., Int J Parasitol Drugs Drug Resist. December 1, 2018; 8 (3): 540-549.                          


Structural basis of neurosteroid anesthetic action on GABAA receptors., Chen Q, Wells MM, Arjunan P, Tillman TS, Cohen AE, Xu Y, Xu Y, Tang P., Nat Commun. September 28, 2018; 9 (1): 3972.              


Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor., Smelt CLC, Sanders VR, Newcombe J, Burt RP, Sheppard TD, Topf M, Millar NS., Neuropharmacology. September 1, 2018; 139 194-204.                


The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease., Furutani S, Ihara M, Lees K, Buckingham SD, Partridge FA, David JA, Patel R, Warchal S, Mellor IR, Matsuda K, Sattelle DB., Int J Parasitol Drugs Drug Resist. August 1, 2018; 8 (2): 350-360.                


LY2087101 and dFBr share transmembrane binding sites in the (α4)3(β2)2 Nicotinic Acetylcholine Receptor., Deba F, Ali HI, Tairu A, Ramos K, Ali J, Hamouda AK., Sci Rep. January 19, 2018; 8 (1): 1249.                      


Identification and Functional Analysis of the First Aquaporin from Striped Stem Borer, Chilo suppressalis., Lu MX, Pan DD, Xu J, Liu Y, Wang GR, Du YZ., Front Physiol. January 1, 2018; 9 57.              


Inward- and outward-facing homology modeling of human concentrative nucleoside transporter 3 (hCNT3) predicts an elevator-type transport mechanism., Yao SYM, Young JD., Channels (Austin). January 1, 2018; 12 (1): 291-298.        


Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1., Gorraitz E, Hirayama BA, Paz A, Wright EM, Loo DDF., Proc Natl Acad Sci U S A. November 14, 2017; 114 (46): E9980-E9988.            


A Single Amino Acid Substitution in the Third Transmembrane Region Has Opposite Impacts on the Selectivity of the Parasiticides Fluralaner and Ivermectin for Ligand-Gated Chloride Channels., Nakata Y, Fuse T, Yamato K, Asahi M, Nakahira K, Ozoe F, Ozoe Y., Mol Pharmacol. November 1, 2017; 92 (5): 546-555.


Orthosteric- versus allosteric-dependent activation of the GABAA receptor requires numerically distinct subunit level rearrangements., Amin J, Subbarayan MS., Sci Rep. August 10, 2017; 7 (1): 7770.            


Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance., Mulinta R, Yao SYM, Ng AML, Cass CE, Young JD., J Biol Chem. June 9, 2017; 292 (23): 9505-9522.                    


Probing the Structural Mechanism of Partial Agonism in Glycine Receptors Using the Fluorescent Artificial Amino Acid, ANAP., Soh MS, Estrada-Mondragon A, Durisic N, Keramidas A, Lynch JW., ACS Chem Biol. March 17, 2017; 12 (3): 805-813.


Molecular Mechanism of AMPA Receptor Modulation by TARP/Stargazin., Ben-Yaacov A, Gillor M, Haham T, Parsai A, Qneibi M, Stern-Bach Y., Neuron. March 8, 2017; 93 (5): 1126-1137.e4.


Synergistic and compensatory effects of two point mutations conferring target-site resistance to fipronil in the insect GABA receptor RDL., Zhang Y, Meng X, Yang Y, Li H, Wang X, Yang B, Zhang J, Li C, Millar NS, Liu Z., Sci Rep. August 25, 2016; 6 32335.          


Potentiation of Gamma Aminobutyric Acid Receptors (GABAAR) by Ethanol: How Are Inhibitory Receptors Affected?, Förstera B, Castro PA, Moraga-Cid G, Aguayo LG., Front Cell Neurosci. May 6, 2016; 10 114.    


Inter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor., McCracken ML, Gorini G, McCracken LM, Mayfield RD, Harris RA, Trudell JR., Front Mol Neurosci. February 15, 2016; 9 45.              


Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2., Subramanian N, Scopelitti AJ, Carland JE, Ryan RM, O'Mara ML, Vandenberg RJ., PLoS One. January 1, 2016; 11 (6): e0157583.            


Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes., Courtot E, Charvet CL, Beech RN, Harmache A, Wolstenholme AJ, Holden-Dye L, O'Connor V, Peineau N, Woods DJ, Neveu C., PLoS Pathog. December 1, 2015; 11 (12): e1005267.                


Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32., Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Perez-Acle T, Skerrett IM., J Biol Chem. July 10, 2015; 290 (28): 17074-84.


Identification of the first sodium binding site of the phosphate cotransporter NaPi-IIa (SLC34A1)., Fenollar-Ferrer C, Forster IC, Patti M, Knoepfel T, Werner A, Forrest LR., Biophys J. May 19, 2015; 108 (10): 2465-2480.


Potentiation of Neuronal Nicotinic Receptors by 17β-Estradiol: Roles of the Carboxy-Terminal and the Amino-Terminal Extracellular Domains., Jin X, Steinbach JH., PLoS One. January 1, 2015; 10 (12): e0144631.        


Exon 3 splicing and mutagenesis identify residues influencing cell surface density of heterologously expressed silkworm (Bombyx mori) glutamate-gated chloride channels., Furutani S, Ihara M, Nishino Y, Akamatsu M, Jones AK, Sattelle DB, Matsuda K., Mol Pharmacol. December 1, 2014; 86 (6): 686-95.


Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation., Brosnan RJ, Pham TL., BMC Pharmacol Toxicol. November 19, 2014; 15 62.          


Impact of intracellular domain flexibility upon properties of activated human 5-HT3 receptors., Kozuska JL, Paulsen IM, Belfield WJ, Martin IL, Cole DJ, Holt A, Dunn SM., Br J Pharmacol. April 1, 2014; 171 (7): 1617-28.      


Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps., Vedovato N, Gadsby DC., J Gen Physiol. April 1, 2014; 143 (4): 449-64.                  


GABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sites., Borghese CM, Hicks JA, Lapid DJ, Trudell JR, Harris RA., J Neurochem. February 1, 2014; 128 (3): 363-75.


Structural model of the anion exchanger 1 (SLC4A1) and identification of transmembrane segments forming the transport site., Barneaud-Rocca D, Etchebest C, Guizouarn H., J Biol Chem. September 13, 2013; 288 (37): 26372-84.


The relative orientation of the TM3 and TM4 domains varies between α1 and α3 glycine receptors., Han L, Talwar S, Lynch JW., ACS Chem Neurosci. February 20, 2013; 4 (2): 248-54.


Analysis of trafficking, stability and function of human connexin 26 gap junction channels with deafness-causing mutations in the fourth transmembrane helix., Ambrosi C, Walker AE, Depriest AD, Cone AC, Lu C, Badger J, Skerrett IM, Sosinsky GE., PLoS One. January 1, 2013; 8 (8): e70916.                        


The importance of being aromatic: π interactions in sodium symporters., Jiang X, Loo DD, Hirayama BA, Wright EM., Biochemistry. November 27, 2012; 51 (47): 9480-7.


The N-terminal half of the connexin protein contains the core elements of the pore and voltage gates., Kronengold J, Srinivas M, Verselis VK., J Membr Biol. August 1, 2012; 245 (8): 453-63.


Cystic fibrosis transmembrane conductance regulator: a molecular model defines the architecture of the anion conduction path and locates a "bottleneck" in the pore., Norimatsu Y, Ivetac A, Alexander C, Kirkham J, O'Donnell N, Dawson DC, Sansom MS., Biochemistry. March 20, 2012; 51 (11): 2199-212.


Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols., Borghese CM, Blednov YA, Quan Y, Iyer SV, Xiong W, Mihic SJ, Zhang L, Lovinger DM, Trudell JR, Homanics GE, Harris RA., J Pharmacol Exp Ther. February 1, 2012; 340 (2): 304-16.


Competitive binding at a nicotinic receptor transmembrane site of two α7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization., Collins T, Young GT, Millar NS., Neuropharmacology. December 1, 2011; 61 (8): 1306-13.              


Conserved residues in the extracellular loops of short-wavelength cone visual pigments., Chen MH, Sandberg DJ, Babu KR, Bubis J, Surya A, Ramos LS, Zapata HJ, Galan JF, Sandberg MN, Birge RR, Knox BE., Biochemistry. August 16, 2011; 50 (32): 6763-73.


A mutant residue in the third transmembrane region of the GABA(A) alpha1 subunit causes increased agonistic neurosteroid responses., Williams DB., Neurochem Int. June 1, 2011; 58 (7): 794-803.


Mutations in the transmembrane domain M3 generate spontaneously open orphan glutamate δ1 receptor., Yadav R, Rimerman R, Scofield MA, Dravid SM., Dev Biol. March 25, 2011; 1382 1-8.


Ligand- and subunit-specific conformational changes in the ligand-binding domain and the TM2-TM3 linker of {alpha}1 {beta}2 {gamma}2 GABAA receptors., Wang Q, Pless SA, Lynch JW., J Biol Chem. December 17, 2010; 285 (51): 40373-86.


SCAM analysis of Panx1 suggests a peculiar pore structure., Wang J, Dahl G., J Gen Physiol. November 1, 2010; 136 (5): 515-27.                  


Nicotinic acetylcholine receptor transmembrane mutations convert ivermectin from a positive to a negative allosteric modulator., Collins T, Millar NS., Mol Pharmacol. August 1, 2010; 78 (2): 198-204.

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