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Summary Expression Phenotypes Gene Literature (22) GO Terms (10) Nucleotides (84) Proteins (37) Interactants (42) Wiki

Papers associated with grik1

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1 paper(s) referencing morpholinos

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Structure and assembly mechanism for heteromeric kainate receptors., Kumar J, Schuck P, Mayer ML., Neuron. July 28, 2011; 71 (2): 319-31.

Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning., Fakhro KA, Choi M, Ware SM, Belmont JW, Towbin JA, Lifton RP, Khokha MK, Brueckner M., Proc Natl Acad Sci U S A. February 15, 2011; 108 (7): 2915-20.                      

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization., Clausen RP, Naur P, Kristensen AS, Greenwood JR, Strange M, Bräuner-Osborne H, Jensen AA, Nielsen AS, Geneser U, Ringgaard LM, Nielsen B, Pickering DS, Brehm L, Gajhede M, Krogsgaard-Larsen P, Kastrup JS., J Med Chem. August 13, 2009; 52 (15): 4911-22.

Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists., Mayer ML, Ghosal A, Dolman NP, Jane DE., J Neurosci. March 15, 2006; 26 (11): 2852-61.

Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: synthesis, modelling and molecular pharmacology., Frølund B, Greenwood JR, Holm MM, Egebjerg J, Madsen U, Nielsen B, Bräuner-Osborne H, Stensbøl TB, Krogsgaard-Larsen P., Bioorg Med Chem. September 15, 2005; 13 (18): 5391-8.

(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology., Brehm L, Greenwood JR, Hansen KB, Nielsen B, Egebjerg J, Stensbøl TB, Bräuner-Osborne H, Sløk FA, Kronborg TT, Krogsgaard-Larsen P., J Med Chem. April 10, 2003; 46 (8): 1350-8.

The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741., Nielsen MM, Liljefors T, Krogsgaard-Larsen P, Egebjerg J., Mol Pharmacol. January 1, 2003; 63 (1): 19-25.

Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy., Palma E, Esposito V, Mileo AM, Di Gennaro G, Quarato P, Giangaspero F, Scoppetta C, Onorati P, Trettel F, Miledi R, Eusebi F., Proc Natl Acad Sci U S A. November 12, 2002; 99 (23): 15078-83.

Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist., Stensbøl TB, Jensen HS, Nielsen B, Johansen TN, Egebjerg J, Frydenvang K, Krogsgaard-Larsen P., Eur J Pharmacol. January 12, 2001; 411 (3): 245-53.

Resolution, configurational assignment, and enantiopharmacology of 2-amino-3-[3-hydroxy-5-(2-methyl-2H- tetrazol-5-yl)isoxazol-4-yl]propionic acid, a potent GluR3- and GluR4-preferring AMPA receptor agonist., Vogensen SB, Jensen HS, Stensbøl TB, Frydenvang K, Bang-Andersen B, Johansen TN, Egebjerg J, Krogsgaard-Larsen P., Chirality. November 1, 2000; 12 (10): 705-13.

Resolution, absolute stereochemistry and molecular pharmacology of the enantiomers of ATPA., Stensbøl TB, Borre L, Johansen TN, Egebjerg J, Madsen U, Ebert B, Krogsgaard-Larsen P., Eur J Pharmacol. September 10, 1999; 380 (2-3): 153-62.

Acute effects of ethanol on kainate receptors with different subunit compositions., Valenzuela CF, Cardoso RA., J Pharmacol Exp Ther. March 1, 1999; 288 (3): 1199-206.

Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid., Møller EH, Egebjerg J, Brehm L, Stensbøl TB, Johansen TN, Madsen U, Krogsgaard-Larsen P., Chirality. January 1, 1999; 11 (10): 752-9.

Pharmacology and toxicology of ATOA, an AMPA receptor antagonist and a partial agonist at GluR5 receptors., Wahl P, Frandsen A, Madsen U, Schousboe A, Krogsgaard-Larsen P., Neuropharmacology. October 1, 1998; 37 (10-11): 1205-10.

The methylglutamate, SYM 2081, is a potent and highly selective agonist at kainate receptors., Donevan SD, Beg A, Gunther JM, Twyman RE., J Pharmacol Exp Ther. May 1, 1998; 285 (2): 539-45.

Antagonist properties of a phosphono isoxazole amino acid at glutamate R1-4 (R,S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor subtypes., Wahl P, Anker C, Traynelis SF, Egebjerg J, Rasmussen JS, Krogsgaard-Larsen P, Madsen U., Mol Pharmacol. March 1, 1998; 53 (3): 590-6.

Structure and pharmacological properties of a molluscan glutamate-gated cation channel and its likely role in feeding behavior., Stühmer T, Amar M, Harvey RJ, Bermudez I, van Minnen J, Darlison MG., J Neurosci. May 1, 1996; 16 (9): 2869-80.

New developments in the molecular pharmacology of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate and kainate receptors., Fletcher EJ, Lodge D., Pharmacol Ther. January 1, 1996; 70 (1): 65-89.

Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A., Partin KM, Patneau DK, Winters CA, Mayer ML, Buonanno A., Neuron. December 1, 1993; 11 (6): 1069-82.

Cloning of a putative glutamate receptor: a low affinity kainate-binding subunit., Bettler B, Egebjerg J, Sharma G, Pecht G, Hermans-Borgmeyer I, Moll C, Stevens CF, Heinemann S., Neuron. February 1, 1992; 8 (2): 257-65.

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA., Egebjerg J, Bettler B, Hermans-Borgmeyer I, Heinemann S., Nature. June 27, 1991; 351 (6329): 745-8.

Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development., Bettler B, Boulter J, Hermans-Borgmeyer I, O'Shea-Greenfield A, Deneris ES, Moll C, Borgmeyer U, Hollmann M, Heinemann S., Neuron. November 1, 1990; 5 (5): 583-95.

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