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XB-GENEPAGE-478788
tbxt T-box transcription factor T
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| decreased length of anterior-posterior axis (4 sources), abnormal gastrulation (3 sources), abnormal head morphology (3 sources), abnormally delayed closure of blastopore (2 sources), abnormal tail morphology (2 sources), abnormal bending of anterior-posterior axis (1 source), abnormal bending of tail (1 source), abnormal incomplete closing of the neural tube (1 source), abnormally anterioralized embryo (1 source), abnormal tail bud morphology (1 source), decreased size of the head (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: tbxt assayed (116 sources) |
| Computed annotations: tbxt manipulated (6 sources), tbxt assayed (36 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xtr Wt + tbxt MO (3 sources), Xtr Wt + tbxt MO (3 sources), Xtr Wt + vegt MO + eomes MO + tbxt MO + tbxt.2 MO (3 sources), Xtr.Wt + tbxt MO + tbxt.2 MO (2 sources), Xla Wt + dntbxt-EnR (1 source), Xtr Wt + tbxt MO + tbxt.2 MO (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (2 sources): Abnormal vertebral morphology, Absence of the sacrum |
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View all ortholog results at Monarch |