arpc1b Phenotypes

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Phenotypes

Gene Literature (2)

Nucleotides (541)

Interactants (321)

XB-GENEPAGE-490409

Gene Symbol: arpc1b Gene Name: actin related protein 2/3 complex subunit 1B

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (9 sources): Decreased mean platelet volume, Elevated erythrocyte sedimentation rate, Failure to thrive, Increased total lymphocyte count, Inflammation of the large intestine, Lymphadenopathy, Recurrent infections, Thrombocytopenia, Vasculitis
Mouse (26 sources): abnormal bone mineralization, abnormal circulating fructosamine level, decreased bone mineral content, decreased CD4-positive, alpha beta T cell number, decreased circulating fructosamine level, decreased KLRG1-positive NK cell number, decreased Ly6C-positive mature NK cell number, decreased macrophage cell number, decreased marginal zone precursor B cell number, decreased mature NK cell number, decreased transitional stage T2 B cell number, fusion of vertebral arches, increased CD103-positive CD11b-low dendritic cell number, increased CD4-positive, alpha-beta memory T cell number, increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased effector memory T-helper cell number, increased immature NK cell number, increased KLRG1+ CD4 alpha beta T cell number, increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased KLRG1-positive T-helper cell number, increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased memory-marker CD4-negative NK T cell number, increased memory-marker NK cell number, increased plasma cell number, pigment incontinence, skin fibrosis [+]
View all ortholog results at Monarch