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XB-GENEPAGE-495260
id3 inhibitor of DNA binding 3, HLH protein
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| decreased length of anterior-posterior axis (2 sources), abnormally neoplastic epidermis (1 source), decreased size of the head (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: id3 assayed (1 source) |
| Computed annotations: id3 assayed (3 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xtr Wt + id3 MO (1 source), Xtr Wt + id3 MO (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (17 sources): abnormal double-positive T cell morphology, abnormal T cell differentiation, decreased B cell proliferation, decreased CD4-positive, alpha beta T cell number, decreased salivation, decreased thymocyte number, immune system phenotype, increased autoantibody level, increased CD4-positive, alpha-beta memory T cell number, increased CD8-positive, alpha-beta memory T cell number, [+] |