nlgn2 Phenotypes

PhenotypesPheno.

XB-GENEPAGE-6034905

Gene Symbol: nlgn2 Gene Name: neuroligin 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: nlgn2 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (29 sources): abnormal brain wave pattern, abnormal CNS synaptic transmission, abnormal hippocampus physiology, abnormal inhibitory postsynaptic currents, abnormal miniature inhibitory postsynaptic currents, abnormal postsynaptic density morphology, abnormal response to novelty, abnormal social investigation, abnormal spatial working memory, abnormal synapse morphology, behavior/neurological phenotype, decreased anxiety-related response, decreased freezing behavior, decreased prepulse inhibition, decreased startle reflex, impaired contextual conditioning behavior, impaired cued conditioning behavior, increased anxiety-related response, increased excitatory postsynaptic current amplitude, increased startle reflex, increased thigmotaxis, increased vertical activity, induced hyperactivity, limb grasping, nervous system phenotype, premature death, slow postnatal weight gain, social withdrawal, straub tail [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (29 sources): abnormal brain wave pattern, abnormal CNS synaptic transmission, abnormal hippocampus physiology, abnormal inhibitory postsynaptic currents, abnormal miniature inhibitory postsynaptic currents, abnormal postsynaptic density morphology, abnormal response to novelty, abnormal social investigation, abnormal spatial working memory, abnormal synapse morphology, [+]