vav2 Phenotypes

PhenotypesPheno.

XB-GENEPAGE-6067165

Gene Symbol: vav2 Gene Name: vav guanine nucleotide exchange factor 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: vav2 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (24 sources): abnormal adrenal gland secretion, abnormal aorta tunica media morphology, abnormal bradykinin level, abnormal class switch recombination, abnormal iridocorneal angle, abnormal physiological response to xenobiotic, adrenal medulla hyperplasia, cardiac fibrosis, decreased B cell proliferation, decreased IgG1 level, decreased IgG2b level, decreased IgG3 level, decreased mature B cell number, decreased spleen germinal center number, decreased urine sodium level, enlarged adrenal medulla, enlarged myocardial fiber, increased circulating adrenaline level, increased circulating antidiuretic hormone level, increased circulating noradrenaline level, increased mean systemic arterial blood pressure, increased renin activity, ocular hypertension, vascular smooth muscle hyperplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (24 sources): abnormal adrenal gland secretion, abnormal aorta tunica media morphology, abnormal bradykinin level, abnormal class switch recombination, abnormal iridocorneal angle, abnormal physiological response to xenobiotic, adrenal medulla hyperplasia, cardiac fibrosis, decreased B cell proliferation, decreased IgG1 level, [+]