| Monarch Ortholog Phenotypes
|
Human (23 sources):
Coloboma,
Cutaneous photosensitivity,
Episodic hemolytic anemia,
Freckling,
Generalized muscle weakness,
Hand tremor,
Hearing impairment,
Hyperkalemia,
Hypermelanotic macule,
Hypertension,
Hypopigmented macule,
Hypopigmented skin patches,
Increased mean corpuscular volume,
Macular coloboma,
Macule,
Microphthalmia,
Multiple cafe-au-lait spots,
Muscle spasm,
Periodic paralysis,
Reticulocytosis,
Short stature,
Spotty hypopigmentation,
Stomatocytosis
[+]
|
|
Mouse (9 sources):
abnormal circulating cholesterol level,
abnormal erythropoiesis,
abnormal mitochondrial physiology,
abnormal vibrissa morphology,
decreased circulating alkaline phosphatase level,
decreased physiological sensitivity to xenobiotic,
increased physiological sensitivity to xenobiotic,
increased sensitivity to xenobiotic induced morbidity/mortality,
lethality, incomplete penetrance
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.