Monarch Ortholog Phenotypes
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Mouse (39 sources):
abnormal cell migration,
abnormal diaphragm development,
abnormal epidermis stratum granulosum morphology,
abnormal extraembryonic tissue morphology,
abnormal hair follicle development,
abnormal keratinocyte physiology,
abnormal lipid homeostasis,
abnormal muscle precursor cell migration,
abnormal muscle precursor cell morphology,
abnormal myogenesis,
abnormal placenta labyrinth morphology,
abnormal placenta vasculature,
abnormal skeletal muscle morphology,
decreased circulating free fatty acids level,
decreased circulating glucose level,
decreased embryo size,
decreased glycogen level,
decreased liver weight,
decreased skeletal muscle mass,
decreased trophoblast giant cell number,
dilated heart left ventricle,
disorganized placental labyrinth,
early eyelid opening,
embryonic lethality during organogenesis, incomplete penetrance,
eyelids open at birth,
fetal growth retardation,
hypaxial muscle hypoplasia,
impaired wound healing,
improved glucose tolerance,
increased insulin sensitivity,
lethality throughout fetal growth and development, complete penetrance,
muscle phenotype,
palatal shelves fail to meet at midline,
placental labyrinth hypoplasia,
postnatal lethality, incomplete penetrance,
thin epidermis,
thin placenta labyrinth,
thin ventricular wall,
ventricular hypoplasia
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