Behavioral abnormality, Bowel incontinence, Cachexia, Cerebral cortical atrophy, Cerebral dysmyelination, Choreoathetosis, Cognitive impairment, Congenital laryngeal stridor, Degeneration of the lateral corticospinal tracts, Delayed speech and language development, Developmental regression, Dysarthria, Dysmetria, Dysphagia, Dystonia, Failure to thrive, Failure to thrive in infancy, Flexion contracture, Gait disturbance, Generalized hypotonia, Global developmental delay, Head titubation, Hearing impairment, Hyperreflexia, Hyporeflexia, Intellectual disability, Joint stiffness, Kyphosis, Limitation of joint mobility, Lower limb muscle weakness, Lower limb spasticity, Microcephaly, Muscle weakness, Muscular hypotonia, Neurological speech impairment, Nystagmus, Optic atrophy, Peripheral neuropathy, Pes cavus, Premature birth, Progressive spastic quadriplegia, Psychomotor deterioration, Pulmonary embolism, Recurrent respiratory infections, Reduction of oligodendroglia, Respiratory insufficiency, Rotary nystagmus, Scanning speech, Scoliosis, Seizure, Sensory neuropathy, Short stature, Skeletal muscle atrophy, Spastic gait, Spastic paraparesis, Spastic paraplegia, Spastic/hyperactive bladder, Spasticity, Spinocerebellar tract degeneration, Sudanophilic leukodystrophy, Tremor, Visual impairment

abnormal glial cell morphology, abnormal hippocampal fimbria morphology, abnormal locomotor coordination, abnormal microglial cell morphology, abnormal myelin sheath morphology, abnormal oligodendrocyte apoptosis, abnormal optic tract morphology, abnormal startle reflex, asthenozoospermia, axonal spheroids, behavior/neurological phenotype, decreased cholesterol level, decreased myelin sheath thickness, decreased oligodendrocyte number, decreased susceptibility to Picornaviridae infection, decreased vocalization, delayed eyelid opening, environmentally induced seizures, growth/size/body region phenotype, hindlimb paralysis, hypoactivity, increased apoptosis, increased oligodendrocyte number, lethality at weaning, complete penetrance, microgliosis, nervous system phenotype, postnatal lethality, complete penetrance, premature death, reproductive system phenotype, tomacula