slc3a2 Phenotypes

Phenotypes

XB-GENEPAGE-1009244

Gene Symbol: slc3a2 Gene Name: solute carrier family 3 (amino acid transporter heavy chain), member 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: slc3a2 assayed (9 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (20 sources): abnormal B cell activation, abnormal cell morphology, abnormal class switch recombination, abnormal enterocyte proliferation, abnormal macrophage antigen presentation, abnormal macrophage differentiation, abnormal macrophage physiology, abnormal plasma cell differentiation, decreased B cell proliferation, decreased IgG3 level, decreased germinal center B cell number, decreased incidence of tumors by chemical induction, decreased sensitivity to xenobiotic induced morbidity/mortality, decreased susceptibility to induced colitis, decreased susceptibility to weight loss, decreased tumor growth/size, embryonic lethality, complete penetrance, immune system phenotype, impaired macrophage phagocytosis, preweaning lethality, incomplete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (20 sources): abnormal B cell activation, abnormal cell morphology, abnormal class switch recombination, abnormal enterocyte proliferation, abnormal macrophage antigen presentation, abnormal macrophage differentiation, abnormal macrophage physiology, abnormal plasma cell differentiation, decreased B cell proliferation, decreased IgG3 level, [+]