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Summary Expression Phenotypes Gene Literature (25) GO Terms (11) Nucleotides (902) Proteins (44) Interactants (280) Wiki
XB-GENEPAGE-1009629

sparc     secreted protein, acidic, cysteine-rich (osteonectin)

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sparc assayed (16 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (25 sources): Biconcave flattened vertebrae, Blue sclerae, Bowing of limbs due to multiple fractures, Decreased muscle mass, Delayed speech and language development, Dentinogenesis imperfecta, Femoral bowing present at birth, straightening with time, Hearing impairment, Increased susceptibility to fractures, Intraventricular hemorrhage, [+]
Mouse (26 sources): abnormal bone remodeling, abnormal bone strength, abnormal humerus morphology, abnormal incisor color, abnormal lens capsule morphology, abnormal lens epithelium morphology, abnormal lens fiber morphology, abnormal osteoblast morphology, abnormal osteoclast morphology, abnormal retinal layer morphology, [+]

View all ortholog results at Monarch