mttp Phenotypes

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Phenotypes

Gene Literature (8)

Nucleotides (98)

Interactants (39)

XB-GENEPAGE-1011747

Gene Symbol: mttp Gene Name: microsomal triglyceride transfer protein, gene 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: mttp assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (14 sources): Abetalipoproteinemia, Abnormality of movement, Abnormality of retinal pigmentation, Acanthocytosis, Ataxia, CNS demyelination, Fat malabsorption, Hypotonia, Malabsorption, Peripheral demyelination, Reduced tendon reflexes, Retinal degeneration, Retinopathy, Visual impairment [+]
Mouse (17 sources): abnormal circulating cholesterol level, abnormal circulating lipid level, abnormal lipid homeostasis, abnormal lipid level, abnormal triglyceride level, abnormal visceral yolk sac blood island morphology, abnormal visceral yolk sac endoderm morphology, decreased circulating VLDL triglyceride level, decreased erythrocyte cell number, embryo tissue necrosis, embryonic growth retardation, embryonic lethality during organogenesis, incomplete penetrance, incomplete rostral neuropore closure, increased liver cholesterol level, increased liver triglyceride level, increased liver weight, pale yolk sac [+]
View all ortholog results at Monarch