fan1 Phenotypes

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Phenotypes

Gene Literature (4)

Nucleotides (84)

Interactants (40)

XB-GENEPAGE-1011795

Gene Symbol: fan1 Gene Name: FANCD2/FANCI-associated nuclease 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (58 sources): Abdominal pain, Abnormal pyramidal sign, Agnosia, Amaurosis fugax, Anxiety, Attention deficit hyperactivity disorder, Basal cell carcinoma, Behavioral abnormality, Benign neoplasm of the central nervous system, Cardiac diverticulum, Colon cancer, Constipation, Depression, Developmental regression, Dysarthria, Dysgraphia, Dyskinesia, Elevated circulating creatinine concentration, Elevated circulating hepatic transaminase concentration, Fatigue, Flexion contracture, Gait disturbance, Gastrointestinal hemorrhage, Glioblastoma multiforme, Glycosuria, Hallucinations, Hematuria, Hemiplegia/hemiparesis, Hepatocellular carcinoma, Hypotonia, Increased blood urea nitrogen, Increased intracranial pressure, Intestinal polyposis, Irritability, Malabsorption, Memory impairment, Migraine, Nausea and vomiting, Neoplasm of the pancreas, Neoplasm of the rectum, Neoplasm of the skeletal system, Neoplasm of the thyroid gland, Nephronophthisis, Neuroblastoma, Neurological speech impairment, Ovarian neoplasm, Pancreatic adenocarcinoma, Paresthesia, Pituitary adenoma, Proteinuria, Seizure, Spasticity, Stage 5 chronic kidney disease, Tubulointerstitial nephritis, Urinary tract neoplasm, Visual field defect, Visual impairment, Weight loss [+]
Mouse (14 sources): abnormal cell nucleus morphology, abnormal hematopoietic stem cell physiology, abnormal renal tubule epithelium morphology, abnormal renal tubule morphology, dilated renal tubules, hematopoietic system phenotype, increased cellular sensitivity to alkylating agents, increased hepatocyte karyomegaly, increased kidney cell proliferation, increased physiological sensitivity to xenobiotic, increased sensitivity to induced cell death, increased sensitivity to xenobiotic induced morbidity/mortality, polyploidy, renal/urinary system phenotype [+]
View all ortholog results at Monarch