| Monarch Ortholog Phenotypes
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Human (10 sources):
Bronchiectasis,
Chronic lung disease,
Decreased circulating immunoglobulin concentration,
Diarrhea,
Failure to thrive,
Gastritis,
Inflammation of the large intestine,
Recurrent infections,
Recurrent respiratory infections,
Skin rash
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Mouse (14 sources):
abnormal body temperature,
abnormal brown adipose tissue morphology,
abnormal brown adipose tissue physiology,
abnormal colon morphology,
abnormal dermal layer morphology,
abnormal immune system organ morphology,
abnormal thymus morphology,
decreased sensitivity to induced cell death,
decreased thymocyte number,
increased cell death,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.