rptor Phenotypes

Summary

Expression

Phenotypes

Gene Literature (1)

XB-GENEPAGE-1012817

Gene Symbol: rptor Gene Name: regulatory associated protein of MTOR, complex 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (52 sources): abnormal Sertoli cell barrier morphology, abnormal cell cytoskeleton morphology, abnormal cell differentiation, abnormal hepatocyte morphology, abnormal male germ cell physiology, abnormal muscle cell glucose uptake, abnormal peritubular myoid cell morphology, abnormal seminiferous tubule epithelium morphology, abnormal seminiferous tubule morphology, abnormal spermatid morphology, abnormal spermiogenesis, abnormal testis development, abnormal trophoblast giant cell morphology, decreased Sertoli cell number, decreased brown adipose tissue amount, decreased circulating glucose level, decreased colon length, decreased epididymis weight, decreased inner cell mass proliferation, decreased litter size, decreased liver triglyceride level, decreased locomotor activity, decreased male germ cell number, decreased muscle weight, decreased susceptibility to diet-induced obesity, decreased testis weight, decreased total fat pad weight, decreased white fat cell number, decreased white fat cell size, digestive/alimentary phenotype, ectopic Sertoli cells, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality prior to tooth bud stage, embryonic lethality, complete penetrance, homeostasis/metabolism phenotype, impaired exercise endurance, improved glucose tolerance, increased circulating ketone body level, increased dendritic cell number, increased lean body mass, increased oxygen consumption, increased skeletal muscle glycogen level, increased susceptibility to induced colitis, increased susceptibility to weight loss, increased testis apoptosis, premature death, preweaning lethality, complete penetrance, reduced female fertility, seminiferous tubule degeneration, skeletal muscle interstitial fibrosis, small liver, testis degeneration [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (52 sources): abnormal Sertoli cell barrier morphology, abnormal cell cytoskeleton morphology, abnormal cell differentiation, abnormal hepatocyte morphology, abnormal male germ cell physiology, abnormal muscle cell glucose uptake, abnormal peritubular myoid cell morphology, abnormal seminiferous tubule epithelium morphology, abnormal seminiferous tubule morphology, abnormal spermatid morphology, [+]