rbl2 Phenotypes

Phenotypes

XB-GENEPAGE-1012834

Gene Symbol: rbl2 Gene Name: retinoblastoma-like 2

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased length of anterior-posterior axis (2 sources), abnormal bending of tail (1 source), abnormal head morphology (1 source), abnormal whole organism morphology (1 source), absent eye (1 source), arrested axis elongation (1 source), decreased size of the tail (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: rbl2 assayed (9 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + rbl2 MO (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (27 sources): abnormal cell proliferation, abnormal developmental patterning, abnormal floor plate morphology, abnormal myotome development, abnormal neuron differentiation, absent floor plate, absent hindlimb buds, absent notochord, cardiovascular system phenotype, cellular phenotype, decreased embryo size, embryo phenotype, embryonic growth arrest, embryonic lethality during organogenesis, complete penetrance, failure of heart looping, failure of initiation of embryo turning, growth/size/body region phenotype, incomplete somite formation, increased apoptosis, increased neuron apoptosis, integument phenotype, limbs/digits/tail phenotype, muscle phenotype, nervous system phenotype, no abnormal phenotype detected, preweaning lethality, incomplete penetrance, thin myocardium [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (27 sources): abnormal cell proliferation, abnormal developmental patterning, abnormal floor plate morphology, abnormal myotome development, abnormal neuron differentiation, absent floor plate, absent hindlimb buds, absent notochord, cardiovascular system phenotype, cellular phenotype, [+]