kalrn Phenotypes

Phenotypes

XB-GENEPAGE-1014005

Gene Symbol: kalrn Gene Name: kalirin RhoGEF kinase

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: kalrn assayed (8 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (35 sources): abnormal I band morphology, abnormal Z line morphology, abnormal action potential, abnormal cerebral cortex pyramidal cell morphology, abnormal contextual conditioning behavior, abnormal dendrite morphology, abnormal excitatory postsynaptic currents, abnormal hippocampus pyramidal cell morphology, abnormal maternal behavior, abnormal milk ejection, abnormal miniature excitatory postsynaptic currents, abnormal nest building behavior, abnormal neuromuscular synapse morphology, abnormal neuron physiology, abnormal pituitary secretion, abnormal sarcomere morphology, abnormal spatial working memory, behavior/neurological phenotype, cardiovascular system phenotype, decreased CNS synapse formation, decreased anxiety-related response, decreased body size, decreased physiological sensitivity to xenobiotic, decreased prepulse inhibition, decreased startle reflex, enhanced coordination, homeostasis/metabolism phenotype, impaired passive avoidance behavior, nervous system phenotype, no abnormal phenotype detected, parturition failure, pregnancy-related premature death, preweaning lethality, incomplete penetrance, reduced AMPA-mediated synaptic currents, reduced long term potentiation [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (35 sources): abnormal I band morphology, abnormal Z line morphology, abnormal action potential, abnormal cerebral cortex pyramidal cell morphology, abnormal contextual conditioning behavior, abnormal dendrite morphology, abnormal excitatory postsynaptic currents, abnormal hippocampus pyramidal cell morphology, abnormal maternal behavior, abnormal milk ejection, [+]