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XB-GENEPAGE-1015802
epha4 EPH receptor A4
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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abnormal eye morphology (7 sources), decreased size of the eye (7 sources), abnormal development of eye (3 sources), decreased size of the lens (3 sources), abnormal lens morphology (2 sources), abnormal retina morphology (2 sources), abnormal development of lens (1 source), abnormal development of retinal layer (1 source), abnormal retinal pigmented epithelium morphology (1 source), abnormally localised retinal inner nuclear layer (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: epha4 manipulated (8 sources), epha4 assayed (2 sources) |
Computed annotations: epha4 assayed (16 sources) |
Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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cataract 45 (1AP source) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xla Wt + epha4 MO (14 sources), Xla Wt + epha4 MO (2 sources), Xla Wt + epha4 MO + sipa1l3 MO (1 source), Xla Wt + nog + epha4 MO + animal cap explant (1 source), Xla Wt + Rno.sipa1l3 + epha4 MO (1 source) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Mouse (32 sources): abnormal abducens nerve morphology, abnormal anterior commissure pars anterior morphology, abnormal anterior commissure pars posterior morphology, abnormal axon fasciculation, abnormal axon guidance, abnormal axon morphology, abnormal barrel cortex morphology, abnormal central pattern generator function, abnormal innervation, abnormal innervation pattern to muscle, [+] |