dlg1 Phenotypes

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Phenotypes

Gene Literature (9)

Nucleotides (334)

Interactants (313)

XB-GENEPAGE-1016131

Gene Symbol: dlg1 Gene Name: discs, large homolog 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal swimming behavior (1 source), abnormal tail morphology (1 source), decreased length of anterior-posterior axis (1 source), decreased size of the tail (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + dlg1 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (1 source): Cleft palate
Mouse (56 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal Mullerian duct morphology, abnormal T-helper 1 physiology, abnormal T-helper 2 physiology, abnormal Wolffian duct morphology, abnormal craniofacial morphology, abnormal dendrite morphology, abnormal enterocyte morphology, abnormal kidney development, abnormal lens development, abnormal lens epithelium morphology, abnormal lens fiber morphology, abnormal metanephric mesenchyme morphology, abnormal palatal shelf elevation, abnormal ureter development, abnormal ureter smooth muscle morphology, abnormal ureter urothelium morphology, abnormal ureteric bud morphology, abnormal uterus morphology, absent gastric milk in neonates, absent seminal vesicle, blind uterus, curly tail, decreased body length, decreased body size, decreased embryo weight, decreased fetal size, decreased interferon-gamma secretion, decreased interleukin-2 secretion, decreased lung weight, decreased renal glomerulus number, decreased tumor necrosis factor secretion, dilated kidney collecting duct, dilated ureter, disorganized lens bow, domed cranium, ectopic ovary, fetal growth retardation, hypermyelination, impaired branching involved in ureteric bud morphogenesis, impaired smooth muscle contractility, impaired ureteric peristalsis, increased interleukin-4 secretion, increased interleukin-5 secretion, increased lens epithelium apoptosis, increased lens fiber apoptosis, kinked tail, large ureter, mandible hypoplasia, meteorism, neonatal lethality, complete penetrance, nervous system phenotype, short ureter, small metanephros, ureter hypoplasia, vision/eye phenotype [+]
View all ortholog results at Monarch