wasl Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-1017181

Gene Symbol: wasl Gene Name: WASP like actin nucleation promoting factor

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (50 sources): abnormal allantois morphology, abnormal brain ependyma morphology, abnormal brain vasculature morphology, abnormal cell chemotaxis, abnormal cerebral aqueduct morphology, abnormal cerebral cortex morphology, abnormal choroid plexus morphology, abnormal circulating chemokine level, abnormal dorsal striatum morphology, abnormal ectoplacental cavity morphology, abnormal extraembryonic mesoderm development, abnormal gastrulation, abnormal mesoderm development, abnormal postnatal subventricular zone morphology, abnormal septum of telencephalon morphology, abnormal skin appearance, abnormal spine curvature, absent brain ependyma motile cilia, absent heartbeat, absent hippocampus, decreased body size, decreased corpus callosum size, decreased embryo size, decreased fibroblast proliferation, decreased renal glomerulus number, decreased renal tubule number, delayed embryo turning, dermatitis, dilated esophagus, dilated heart, domed cranium, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, enlarged cranium, epidermal hyperplasia, failure of initiation of embryo turning, impaired skin barrier function, increased brain size, increased circulating interleukin-1 alpha level, increased circulating interleukin-17 level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased keratinocyte proliferation, no abnormal phenotype detected, obstructive hydrocephaly, postnatal lethality, complete penetrance, premature death, prenatal lethality, complete penetrance, thin cerebral cortex, wavy neural tube [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (50 sources): abnormal allantois morphology, abnormal brain ependyma morphology, abnormal brain vasculature morphology, abnormal cell chemotaxis, abnormal cerebral aqueduct morphology, abnormal cerebral cortex morphology, abnormal choroid plexus morphology, abnormal circulating chemokine level, abnormal dorsal striatum morphology, abnormal ectoplacental cavity morphology, [+]