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Summary Expression Phenotypes Gene Literature (242) GO Terms (9) Nucleotides (308) Proteins (39) Interactants (1049) Wiki

smad1     SMAD family member 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal bending of tail (1 source), abnormal gastrulation (1 source), abnormal tail morphology (1 source), abnormally delayed closure of blastopore (1 source), absent head (1 source), decreased length of anterior-posterior axis (1 source), decreased size of the embryo (1 source), decreased size of the eye (1 source), decreased size of the head (1 source), edematous ventral trunk (1 source), wholly ventralized embryo (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: smad1 manipulated (5 sources), smad1 assayed (4 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + smad1 MO (6 sources), Xtr Wt + smad1 MO (3 sources), Xtr Wt + smad1-Rno.GR + DEX (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (51 sources): abnormal allantois morphology, abnormal cell morphology, abnormal chorioallantoic fusion, abnormal chorion morphology, abnormal embryo development, abnormal embryo turning, abnormal embryonic epiblast morphology, abnormal extraembryonic ectoderm morphology, abnormal extraembryonic tissue morphology, abnormal gastric chief cell morphology, [+]