| Monarch Ortholog Phenotypes
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Human (1 source):
Cleft palate
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Mouse (20 sources):
abnormal heart development,
abnormal vascular regression,
decreased B-1b cell number,
decreased CD4-positive, alpha beta T cell number,
decreased common lymphocyte progenitor cell number,
decreased immature B cell number,
decreased pre-B cell number,
decreased pre-pro B cell number,
decreased pro-B cell number,
decreased transitional stage B cell number,
dilated heart,
embryonic growth retardation,
embryonic lethality during organogenesis, complete penetrance,
embryonic lethality, complete penetrance,
hematopoietic system phenotype,
increased B-1a cell number,
increased apoptosis,
increased follicular B cell number,
small pharyngeal arch,
wavy neural tube
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.