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XB-GENEPAGE-12531593
cdh1 cadherin 1, type 1
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal cell migration in neural crest (3 sources), abnormal cell adhesion (1 source), abnormally increased mobility of non-neural ectoderm (1 source), abnormal trachea morphology (1 source), abnormal tracheoesophageal septum (1 source), decreased cell adhesion in mesodermal cell (1 source), decreased size of the branchial arch skeleton (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: cdh1 assayed (15 sources) |
| Computed annotations: cdh1 assayed (12 sources) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| esophageal atresia (1AP source), esophageal atresia/tracheoesophageal fistula (1AP source) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + cdh1 MO (4 sources), Xla Wt + cdh1 MO (1 source), Xla Wt + KD-Pak1 + fn1 MO + cdh3 MO (1 source), Xtr Wt + deltaLL-Cdh1-GFP (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (35 sources): Abnormal eyelid morphology, Abnormal hair quantity, Abnormality of metabolism/homeostasis, Abnormality of the orbital region, Abnormality of vision, Anal atresia, Atrophic gastritis, Breast carcinoma, Carious teeth, Choanal atresia, [+] |
| Mouse (39 sources): abnormal cell adhesion, abnormal embryo development, abnormal embryonic tissue morphology, abnormal enterocyte physiology, abnormal extraembryonic tissue morphology, abnormal mammary gland growth during lactation, abnormal mammary gland growth during pregnancy, abnormal milk composition, abnormal pancreatic islet morphology, abnormal placental labyrinth vasculature morphology, [+] |
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View all ortholog results at Monarch |