Arthralgia, Beaking of vertebral bodies, Bell-shaped thorax, Brachydactyly, Broad ribs, Bulbous nose, Camptodactyly of finger, Cleft palate, Coronal cleft vertebrae, Depressed nasal bridge, Depressed nasal ridge, Downslanted palpebral fissures, Enlarged epiphyses, Enlarged joints, Epiphyseal dysplasia, Exostoses, Feeding difficulties in infancy, Flared metaphysis, Flexion contracture, Glossoptosis, Hearing abnormality, Hyperlordosis, Hypertelorism, Hypoplastic fingernail, Hypoplastic ilia, Hypoplastic ischia, Hypoplastic pubic bone, Hypoplastic scapulae, Joint stiffness, Kyphosis, Large tarsal bones, Long philtrum, Low-set ears, Lumbar hyperlordosis, Malar flattening, Metaphyseal cupping, Metaphyseal widening, Micrognathia, Micromelia, Midface retrusion, Mixed hearing impairment, Narrow chest, Narrow mouth, Omphalocele, Osteoarthritis, Pectus carinatum, Pectus excavatum, Pierre-Robin sequence, Plagiocephaly, Platyspondyly, Premature osteoarthritis, Prominent interphalangeal joints, Proptosis, Protuberant abdomen, Recurrent pneumonia, Respiratory insufficiency, Round face, Sensorineural hearing impairment, Short long bone, Short metacarpal, Short neck, Short nose, Short palm, Short phalanx of finger, Short ribs, Short stature, Strabismus, Synostosis of carpal bones, Thoracic hypoplasia, Ventricular septal defect, Wide anterior fontanel

increased or absent threshold for auditory brainstem response, increased startle reflex, nonsyndromic hearing loss, sensorineural hearing loss