| Monarch Ortholog Phenotypes
|
Human (30 sources):
Abnormal hemoglobin,
Abnormality of immune system physiology,
Abnormality of metabolism/homeostasis,
Anemia,
Cholelithiasis,
Cognitive impairment,
Congestive heart failure,
Cyanosis,
HbH hemoglobin,
Heinz bodies,
Heinz body anemia,
Hemolytic anemia,
Hepatomegaly,
Hydrocephalus,
Hydrops fetalis,
Hypersplenism,
Hypochromic microcytic anemia,
Jaundice,
Methemoglobinemia,
Microcytic anemia,
Myelodysplasia,
Nonspherocytic hemolytic anemia,
Oligohydramnios,
Pallor,
Pericarditis,
Polycythemia,
Polyhydramnios,
Preeclampsia,
Reduced alpha/beta synthesis ratio,
Splenomegaly
[+]
|
|
Mouse (12 sources):
abnormal aerobic respiration,
abnormal mean corpuscular hemoglobin,
abnormal mean corpuscular volume,
abnormal skeletal muscle fiber type ratio,
decreased hemoglobin content,
decreased mean corpuscular hemoglobin,
decreased mean corpuscular volume,
hyperoxia,
increased aerobic running capacity,
increased carbon dioxide production,
[+]
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.