sostdc1 Phenotypes

Phenotypes

XB-GENEPAGE-478255

Gene Symbol: sostdc1 Gene Name: sclerostin domain containing 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sostdc1 assayed (10 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (26 sources): abnormal bone mineralization, abnormal enamel knot morphology, abnormal molar crown morphology, abnormal molar cusp morphology, abnormal osteoblast physiology, abnormal palatal rugae morphology, abnormal palate morphology, abnormal trigeminal ganglion morphology, decreased chondrocyte proliferation, decreased cranium height, decreased osteoclast cell number, decreased physiological sensitivity to xenobiotic, decreased renal tubule apoptosis, decreased sensitivity to xenobiotic induced morbidity/mortality, fused molars, increased bone mass, increased bone mineral content, increased osteoblast cell number, increased osteoblast proliferation, increased trabecular bone volume, neonatal lethality, incomplete penetrance, persistence of hyaloid vascular system, preweaning lethality, incomplete penetrance, short mandible, supernumerary incisors, supernumerary molars [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (26 sources): abnormal bone mineralization, abnormal enamel knot morphology, abnormal molar crown morphology, abnormal molar cusp morphology, abnormal osteoblast physiology, abnormal palatal rugae morphology, abnormal palate morphology, abnormal trigeminal ganglion morphology, decreased chondrocyte proliferation, decreased cranium height, [+]