| Monarch Ortholog Phenotypes
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Human (1 source):
Cleft palate
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Mouse (23 sources):
abnormal axon guidance,
abnormal circulating alkaline phosphatase level,
abnormal ependyma morphology,
abnormal eye development,
abnormal forebrain development,
abnormal lateral ganglionic eminence morphology,
abnormal neuron differentiation,
abnormal olfactory bulb development,
abnormal optic nerve innervation,
abnormal postnatal subventricular zone morphology,
abnormal rostral migratory stream morphology,
abnormal telencephalon development,
abnormal upper incisor morphology,
absent optic chiasm,
decreased circulating glucose level,
decreased startle reflex,
fused upper incisors,
increased circulating alkaline phosphatase level,
lethality at weaning, incomplete penetrance,
neonatal lethality, incomplete penetrance,
perinatal lethality, incomplete penetrance,
premature death,
preweaning lethality, incomplete penetrance
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.