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Summary Expression Phenotypes Gene Literature (54) GO Terms (8) Nucleotides (396) Proteins (56) Interactants (912) Wiki
XB-GENEPAGE-478451

crx     cone-rod homeobox

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal eye morphology (5 sources), abnormal retina morphology (5 sources), absent eye (5 sources), decreased size of the eye (3 sources), abnormal forebrain (1 source), abnormal foregut morphology (1 source), abnormal head morphology (1 source), absent optic stalk (1 source), decreased size of the forebrain (1 source), decreased size of the midbrain-hindbrain boundary (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: crx manipulated (1 source)
Computed annotations: crx assayed (28 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + otx2 MO + crx MO + gsc MO + lhx1 MO (3 sources), Xtr Wt + crx MO (1 source), Xtr Wt + crx MO + otx2 MO (1 source), Xtr Wt + crx MO + otx2 MO + lhx1 MO (1 source), Xtr Wt + gsc MO + crx MO + otx2 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (52 sources): Abnormal electroretinogram, Abnormal retinal vascular morphology, Abnormal testis morphology, Abnormality of fundus pigmentation, Abnormality of neuronal migration, Abnormality of retinal pigmentation, Abnormality of the optic disc, Anteverted nares, Aplasia/Hypoplasia of the cerebellar vermis, Atypical scarring of skin, [+]
Mouse (40 sources): abnormal circadian behavior, abnormal cone electrophysiology, abnormal electroretinogram waveform feature, abnormal eye electrophysiology, abnormal photoreceptor inner segment morphology, abnormal photoreceptor outer segment morphology, abnormal retina bipolar cell morphology, abnormal retina blood vessel morphology, abnormal retina cone bipolar cell morphology, abnormal retina cone cell morphology, [+]

View all ortholog results at Monarch