| Monarch Ortholog Phenotypes
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Human (17 sources):
Abnormality of metabolism/homeostasis,
Central diabetes insipidus,
Diabetes insipidus,
Diarrhea,
Fever,
Gliosis,
Growth delay,
Hypertelorism,
Irritability,
Lethargy,
[+]
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Mouse (11 sources):
abnormal hormone level,
abnormal supraoptic nucleus morphology,
decreased fasting circulating glucose level,
decreased large unstained cell number,
decreased urine osmolality,
impaired righting response,
increased fluid intake,
increased pulmonary respiratory rate,
no abnormal phenotype detected,
postnatal lethality, complete penetrance,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.