| Monarch Ortholog Phenotypes
|
Human (29 sources):
Abnormality of metabolism/homeostasis,
Abnormality of secondary sexual hair,
Abnormality of the uterus,
Aplasia/Hypoplasia of the breasts,
Aplasia/hypoplasia of the uterus,
Arachnodactyly,
Ataxia,
Decreased fertility,
Decreased serum estradiol,
Delayed puberty,
Delayed skeletal maturation,
Gonadal dysgenesis,
Gonadal hypoplasia,
Hearing impairment,
Hirsutism,
Hypergonadotropic hypogonadism,
Hypoplasia of the uterus,
Increased circulating gonadotropin level,
Microcephaly,
Osteopenia,
Osteoporosis of vertebrae,
Premature ovarian insufficiency,
Primary amenorrhea,
Pulmonary fibrosis,
Reduced bone mineral density,
Secondary amenorrhea,
Short stature,
Sparse pubic hair,
Streak ovary
[+]
|
|
Mouse (9 sources):
abnormal oocyte morphology,
abnormal ovarian folliculogenesis,
abnormal zona pellucida morphology,
decreased litter size,
decreased oocyte number,
decreased ovulation rate,
impaired ovarian folliculogenesis,
reduced female fertility,
reproductive system phenotype
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.