nfil3 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (3)

XB-GENEPAGE-479623

Gene Symbol: nfil3 Gene Name: nuclear factor, interleukin 3 regulated

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: nfil3 assayed (8 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (38 sources): abnormal cecum morphology, abnormal circulating cytokine level, abnormal class switch recombination, abnormal colon goblet cell morphology, abnormal colon morphology, abnormal NK cell differentiation, abnormal plasma cell morphology, abnormal thymus morphology, decreased IgG1 level, decreased interferon-gamma secretion, decreased interleukin-10 secretion, decreased interleukin-13 secretion, decreased interleukin-17 secretion, decreased interleukin-4 secretion, decreased interleukin-9 secretion, immune system phenotype, impaired natural killer cell mediated cytotoxicity, improved glucose tolerance, increased circulating interferon-gamma level, increased circulating interleukin-10 level, increased circulating interleukin-12b level, increased circulating interleukin-17 level, increased circulating tumor necrosis factor level, increased interferon-gamma secretion, increased interleukin-10 secretion, increased interleukin-12b secretion, increased interleukin-13 secretion, increased interleukin-17 secretion, increased interleukin-3 secretion, increased macrophage cytokine production, increased memory T cell number, increased NK T cell number, increased susceptibility to experimental autoimmune encephalomyelitis, increased susceptibility to induced colitis, increased T-helper 17 cell number, increased tumor necrosis factor secretion, intestinal ulcer, small thymus [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (38 sources): abnormal cecum morphology, abnormal circulating cytokine level, abnormal class switch recombination, abnormal colon goblet cell morphology, abnormal colon morphology, abnormal NK cell differentiation, abnormal plasma cell morphology, abnormal thymus morphology, decreased IgG1 level, decreased interferon-gamma secretion, [+]