abnormal definitive hematopoiesis, abnormal enzyme/coenzyme level, abnormal gluconeogenesis, abnormal humoral immune response, abnormal innate immunity, abnormal keratinocyte differentiation, abnormal lactation, abnormal lipid homeostasis, abnormal lymph node B cell domain morphology, abnormal lymph node T cell domain morphology, abnormal lymph node cortex morphology, abnormal lymph node medulla morphology, abnormal lymph node medullary cord morphology, abnormal lymph node secondary follicle morphology, abnormal macrophage physiology, abnormal mammary gland development, abnormal mammary gland duct morphology, abnormal mammary gland epithelium physiology, abnormal mucosa-associated lymphoid tissue morphology, abnormal myeloid cell number, abnormal osteoblast physiology, abnormal osteoclast differentiation, abnormal osteoclast morphology, abnormal osteoclast physiology, abnormal plasma cell morphology, abnormal skeletal muscle mass, abnormal spleen red pulp morphology, abnormal spleen secondary B follicle morphology, abnormal spleen white pulp morphology, abnormal tumor necrosis factor level, abnormal zygomatic arch morphology, absent corpus luteum, absent estrous cycle, decreased bone mineralization, decreased bone ossification, decreased bone trabecula number, decreased bone volume, decreased brown adipose tissue amount, decreased cell proliferation, decreased circulating free fatty acids level, decreased circulating interleukin-10 level, decreased circulating interleukin-12 level, decreased epididymal fat pad weight, decreased glycogen catabolism rate, decreased gonadal fat pad weight, decreased incidence of induced tumors, decreased incidence of tumors by chemical induction, decreased insulin secretion, decreased lipoprotein lipase activity, decreased osteoclast cell number, decreased ovulation rate, decreased pancreatic beta cell mass, decreased percent body fat/body weight, decreased sensitivity to induced cell death, decreased skeletal muscle fiber size, decreased susceptibility to bacterial infection, decreased susceptibility to bacterial infection induced morbidity/mortality, decreased susceptibility to endotoxin shock, decreased susceptibility to type IV hypersensitivity reaction, decreased trabecular bone thickness, decreased transforming growth factor beta level, decreased triglyceride level, decreased uterine fat pad weight, enhanced osteoblast differentiation, enlarged axillary lymph nodes, enlarged inguinal lymph nodes, enlarged lymph nodes, enlarged mesenteric lymph nodes, enlarged submandibular lymph nodes, epidermal hyperplasia, granulomatous inflammation, hemosiderosis, homeostasis/metabolism phenotype, impaired adaptive thermogenesis, impaired granulosa cell differentiation, impaired lipolysis, impaired liver regeneration, impaired luteinization, impaired macrophage phagocytosis, impaired ovarian folliculogenesis, impaired skeletal muscle regeneration, increased bone marrow cell number, increased bone mineralization, increased bone ossification, increased bone trabecula number, increased bone volume, increased circulating glucose level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased insulin secretion, increased insulin sensitivity, increased interleukin-12 secretion, increased keratinocyte apoptosis, increased keratinocyte proliferation, increased mesangial cell number, increased muscle cell glucose uptake, increased pancreatic islet cell apoptosis, increased physiological sensitivity to xenobiotic, increased susceptibility to fungal infection, increased trabecular bone thickness, integument phenotype, muscle phenotype, neonatal lethality, incomplete penetrance, no abnormal phenotype detected, perinatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, premature death, prenatal lethality, incomplete penetrance, renal glomerulus hypertrophy, reproductive system phenotype, skeletal muscle fibrosis, skin lesions