abnormal circulating lipid level, abnormal coronary artery morphology, abnormal dendritic spine morphology, abnormal embryo size, abnormal fat pad morphology, abnormal grip strength, abnormal heart echocardiography feature, abnormal heart ventricle outflow tract morphology, abnormal limb bud morphology, abnormal limb posture, abnormal lipid homeostasis, abnormal lipid level, abnormal liver perisinusoidal space morphology, abnormal motor capabilities/coordination/movement, abnormal myocardial fiber morphology, abnormal pericardium morphology, abnormal sleep behavior, abnormal synapse morphology, abnormal vascular smooth muscle physiology, abnormal vascular wound healing, atrioventricular septal defect, cardiac interstitial fibrosis, cardiovascular system phenotype, decreased body surface temperature, decreased brain cholesterol level, decreased brown adipose tissue amount, decreased brown fat cell size, decreased brown fat lipid droplet number, decreased cardiac muscle contractility, decreased circulating free fatty acids level, decreased circulating glucose level, decreased epididymal fat pad weight, decreased exploration in new environment, decreased heart rate variability, decreased hepatocyte number, decreased interscapular fat pad weight, decreased liver triglyceride level, decreased susceptibility to diet-induced obesity, decreased systemic arterial diastolic blood pressure, decreased triglyceride level, decreased vasoconstriction, decreased white fat cell size, dilated heart left ventricle, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, homeostasis/metabolism phenotype, impaired adaptive thermogenesis, impaired contextual conditioning behavior, impaired cued conditioning behavior, impaired limb coordination, improved glucose tolerance, increased circulating factor VIII level, increased circulating von Willebrand factor level, increased energy expenditure, increased food intake, increased heart left ventricle size, increased heart weight, increased muscle cell glucose uptake, increased oxygen consumption, increased pulse pressure, increased susceptibility to weight loss, lethality throughout fetal growth and development, incomplete penetrance, limb grasping, nervous system phenotype, no abnormal phenotype detected, perinatal lethality, complete penetrance, perivascular fibrosis, premature death, preweaning lethality, complete penetrance, reduced fertility, reduced long term potentiation, trunk curl, weakness