irx3 Phenotypes

Phenotypes

XB-GENEPAGE-480485

Gene Symbol: irx3 Gene Name: iroquois homeobox 3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: irx3 assayed (27 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + irx3 + animal cap explant (0 sources), Xtr Wt + irx3 + otx2 + animal cap explant (0 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (16 sources): abnormal QRS complex, abnormal R wave, abnormal atrioventricular bundle conduction, abnormal fasting circulating glucose level, abnormal snout morphology, abnormal white adipose tissue physiology, decreased bone mineral content, decreased fasting circulating glucose level, decreased fat cell size, decreased percent body fat/body weight, decreased susceptibility to diet-induced obesity, decreased susceptibility to hepatic steatosis, improved glucose tolerance, increased energy expenditure, increased insulin sensitivity, prolonged QRS complex duration [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (16 sources): abnormal QRS complex, abnormal R wave, abnormal atrioventricular bundle conduction, abnormal fasting circulating glucose level, abnormal snout morphology, abnormal white adipose tissue physiology, decreased bone mineral content, decreased fasting circulating glucose level, decreased fat cell size, decreased percent body fat/body weight, [+]