foxe3 Phenotypes

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Phenotypes

Gene Literature (26)

Nucleotides (60)

Interactants (202)

XB-GENEPAGE-480591

Gene Symbol: foxe3 Gene Name: forkhead box E3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: foxe3 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (91 sources): Abdominal aortic aneurysm, Abnormal left ventricular function, Abnormal sternum morphology, Abnormality iris morphology, Abnormality of connective tissue, Abnormality of the dentition, Abnormality of the genital system, Abnormality of the hypothalamus-pituitary axis, Abnormality of the sense of smell, Abnormality of vision, Aniridia, Anterior segment of eye aplasia, Anterior synechiae of the anterior chamber, Aortic dissection, Aortic regurgitation, Aortic root aneurysm, Aplasia/Hypoplasia affecting the anterior segment of the eye, Aplasia/Hypoplasia of the corpus callosum, Aplasia/Hypoplasia of the iris, Arachnodactyly, Ascending aortic dissection, Behavioral abnormality, Bicuspid aortic valve, Bruising susceptibility, Cardiomegaly, Carotid artery dilatation, Cataract, Central opacification of the cornea, Chest pain, Coloboma, Congenital aphakia, Corneal erosion, Corneal neovascularization, Corneal opacity, Coronary artery atherosclerosis, Cutis marmorata, Descending aortic dissection, Descending thoracic aorta aneurysm, Developmental glaucoma, Dilatation of the cerebral artery, Dural ectasia, Ectopia lentis, Exertional dyspnea, Glaucoma, Global developmental delay, Hemoptysis, High, narrow palate, Hypertelorism, Hypertension, Hypovolemia, Intellectual disability, Iris hypopigmentation, Ischemic stroke, Keratitis, Keratoconjunctivitis sicca, Keratoconus, Macular hypopigmentation, Macular hypoplasia, Microcornea, Microphthalmia, Mucoid extracellular matrix accumulation, Nystagmus, Ocular hypertension, Opacification of the corneal stroma, Optic disc coloboma, Optic nerve hypoplasia, Paroxysmal dyspnea, Patent ductus arteriosus, Peripheral arterial stenosis, Pes planus, Peters anomaly, Photophobia, Pneumothorax, Posterior synechiae of the anterior chamber, Prenatal maternal abnormality, Ptosis, Retinal dysplasia, Retrognathia, Sclerocornea, Scoliosis, Sensorineural hearing impairment, Short palpebral fissure, Strabismus, Stroke, Subarachnoid hemorrhage, Subcapsular cataract, Tall stature, Thinning of Descemet membrane, Transient ischemic attack, Umbilical hernia, Visual impairment [+]
Mouse (26 sources): abnormal ascending aorta morphology, abnormal canal of Schlemm morphology, abnormal contextual conditioning behavior, abnormal corneal stroma morphology, abnormal iridocorneal angle, abnormal lens development, abnormal lens epithelium morphology, abnormal lens fiber morphology, abnormal lens induction, abnormal lens vesicle development, abnormal pupillary reflex, abnormal response of heart to induced stress, abnormal vascular smooth muscle physiology, absent corneal endothelium, absent trabecular meshwork, corneal-lenticular stalk, decreased corneal epithelium thickness, disorganized secondary lens fibers, eyelids fail to open, fused cornea and lens, hematoma, impaired contextual conditioning behavior, increased sensitivity to induced morbidity/mortality, nervous system phenotype, small pupils, vacuolated lens [+]
View all ortholog results at Monarch