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Summary Expression Phenotypes Gene Literature (107) GO Terms (42) Nucleotides (137) Proteins (31) Interactants (785) Wiki
XB-GENEPAGE-481819

lrp6     LDL receptor related protein 6

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal bending of tail (1 source), abnormally decreased number of melanophore (1 source), decreased size of the anterior-posterior axis (1 source), decreased size of the tail (1 source), increased size of the cement gland (1 source), increased size of the head (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: lrp6 manipulated (1 source)
Computed annotations: lrp6 assayed (8 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + lrp6 MO (2 sources), Xtr Wt + lrp6 MO (1 source), Xtr Wt + lrp6 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (8 sources): Abnormality of dental morphology, Abnormality of the face, Agenesis of permanent teeth, Hypoplasia of the maxilla, Microdontia, Micrognathia, Oligodontia, Taurodontia
Mouse (78 sources): abnormal brown adipose tissue morphology, abnormal caudal vertebrae morphology, abnormal coat appearance, abnormal cranium morphology, abnormal dorsal-ventral polarity of the somites, abnormal external female genitalia morphology, abnormal external male genitalia morphology, abnormal eye development, abnormal fatty acids level, abnormal forebrain development, [+]

View all ortholog results at Monarch