srf Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-482035

Gene Symbol: srf Gene Name: serum response factor

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: srf assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (47 sources): abnormal Z line morphology, abnormal apoptosis, abnormal cardiac muscle relaxation, abnormal diaphragm morphology, abnormal fetal atrioventricular canal morphology, abnormal gastrulation, abnormal heart shape, abnormal intercalated disk morphology, abnormal interventricular groove morphology, abnormal mature B cell morphology, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, abnormal pericardium morphology, absent marginal zone B cells, absent mesoderm, cardiac fibrosis, cardiac hypertrophy, cardiovascular system phenotype, craniofacial phenotype, decreased B-1 B cell number, decreased CD4-positive, alpha beta T cell number, decreased birth weight, decreased embryo size, decreased skeletal muscle mass, decreased thymocyte number, decreased ventricle muscle contractility, dilated heart ventricle, disorganized myocardium, distended pericardium, embryonic growth arrest, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, failure of primitive streak formation, hearing/vestibular/ear phenotype, increased cardiomyocyte apoptosis, increased heart left ventricle size, mandible hypoplasia, neonatal lethality, complete penetrance, no abnormal phenotype detected, no spontaneous movement, postnatal lethality, complete penetrance, premature death, thin interventricular septum, thin myocardium, trabecula carnea hypoplasia, vascular smooth muscle hypotrophy [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (47 sources): abnormal Z line morphology, abnormal apoptosis, abnormal cardiac muscle relaxation, abnormal diaphragm morphology, abnormal fetal atrioventricular canal morphology, abnormal gastrulation, abnormal heart shape, abnormal intercalated disk morphology, abnormal interventricular groove morphology, abnormal mature B cell morphology, [+]