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Summary Expression Phenotypes Gene Literature (92) GO Terms (4) Nucleotides (93) Proteins (30) Interactants (383) Wiki

pkd2     polycystin 2, transient receptor potential cation channel

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pkd2 assayed (6 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (11 sources): Dextrocardia, Elevated circulating creatinine concentration, Facial asymmetry, Hepatic cysts, Hypertension, Midface retrusion, Polycystic kidney dysplasia, Recurrent urinary tract infections, Renal insufficiency, Situs inversus totalis, [+]
Mouse (46 sources): abnormal amniotic fluid composition, abnormal cholangiocyte morphology, abnormal cholangiocyte primary cilium morphology, abnormal direction of embryo turning, abnormal heart development, abnormal heart looping, abnormal hepatic vein morphology, abnormal kidney morphology, abnormal left-right axis patterning, abnormal liver development, [+]

View all ortholog results at Monarch