pax9 Phenotypes

XB-GENEPAGE-482237

Gene Symbol: pax9 Gene Name: paired box 9

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal craniofacial region (4 sources), abnormal head morphology (4 sources), abnormal cartilage element morphology (2 sources), decreased width of the craniofacial region (2 sources), abnormal Meckel's cartilage (1 source), abnormal branchial crest (1 source), abnormal cell migration in neural crest (1 source), abnormal ceratohyal morphology (1 source), abnormal external gill morphology (1 source), abnormal eye morphology (1 source), abnormal hyoid crest (1 source), abnormal mandibular crest (1 source), abnormal pharyngeal arch morphology (1 source), decreased width of the head (1 source), increased apoptosis in epidermis (1 source), increased apoptosis in head region (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

abnormal craniofacial region (4 sources), abnormal head morphology (4 sources), abnormal cartilage element morphology (2 sources), decreased width of the craniofacial region (2 sources), abnormal Meckel's cartilage (1 source), abnormal branchial crest (1 source), abnormal cell migration in neural crest (1 source), abnormal ceratohyal morphology (1 source), abnormal external gill morphology (1 source), abnormal eye morphology (1 source), abnormal hyoid crest (1 source), abnormal mandibular crest (1 source), abnormal pharyngeal arch morphology (1 source), decreased width of the head (1 source), increased apoptosis in epidermis (1 source), increased apoptosis in head region (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: pax9 manipulated (2 sources), pax9 assayed (1 source)
Computed annotations: pax9 assayed (4 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr + pax9 MO (4 sources), Xtr +pax9 CRISPR (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (6 sources): Abnormality of dental morphology, Abnormality of the face, Hypoplasia of the maxilla, Microdontia, Micrognathia, Oligodontia
Mouse (44 sources): abnormal Reichert's cartilage morphology, abnormal ameloblast morphology, abnormal cranium morphology, abnormal dentin development, abnormal hypaxial muscle morphology, abnormal laryngeal cartilage morphology, abnormal limb development, abnormal lower incisor morphology, abnormal mandible morphology, abnormal maxillary shelf morphology, abnormal palatal shelf elevation, abnormal palatine bone horizontal plate morphology, abnormal pharyngeal pouch morphology, abnormal pterygoid process morphology, abnormal secondary palate development, abnormal thymus lobule morphology, abnormal thyroid cartilage morphology, abnormal tooth attrition, abnormal tooth development, abnormal tympanic ring morphology, absent Reichert cartilage, absent alveolar process, absent enamel, absent lower incisors, absent mandibular coronoid process, absent maxillary shelf, absent palatine bone horizontal plate, absent parathyroid glands, absent teeth, absent ultimobranchial body, aphagia, arrest of tooth development, craniofacial phenotype, decreased body size, decreased molar number, decreased tympanic ring size, endocrine/exocrine gland phenotype, failure of palatal shelf elevation, growth retardation of molars, neonatal lethality, complete penetrance, no abnormal phenotype detected, polysyndactyly, postnatal lethality, incomplete penetrance, reproductive system phenotype [+]
View all ortholog results at Monarch