gadd45a Phenotypes

Phenotypes

XB-GENEPAGE-482256

Gene Symbol: gadd45a Gene Name: growth arrest and DNA damage inducible alpha

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gadd45a assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (30 sources): abnormal base-excision repair, abnormal bone marrow cell morphology/development, abnormal cell nucleus morphology, abnormal centrosome morphology, abnormal chromosome morphology, abnormal chromosome number, abnormal lymphopoiesis, abnormal mitosis, aneuploidy, decreased eosinophil cell number, decreased mitotic index, decreased sensitivity to skin irradiation, dilated proximal convoluted tubule, increased IgG1 level, increased T cell proliferation, increased anti-double stranded DNA antibody level, increased anti-histone antibody level, increased anti-single stranded DNA antibody level, increased autoantibody level, increased fibroblast proliferation, increased incidence of tumors by UV-induction, increased incidence of tumors by ionizing radiation induction, increased kidney cell proliferation, increased mesangial cell number, increased sensitivity to skin irradiation, increased thymocyte number, increased thymus weight, mesangial cell interposition, parturition failure, premature death [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (30 sources): abnormal base-excision repair, abnormal bone marrow cell morphology/development, abnormal cell nucleus morphology, abnormal centrosome morphology, abnormal chromosome morphology, abnormal chromosome number, abnormal lymphopoiesis, abnormal mitosis, aneuploidy, decreased eosinophil cell number, [+]