Chronic mucocutaneous candidiasis, Chronic oral candidiasis, Combined immunodeficiency, Cough, Decreased CD3+ T cell proportion, Decreased CD8+ T cell proportion, Decreased circulating IgA concentration, Decreased circulating IgG concentration, Decreased mitogen-induced T-cell proliferation, Decreased proportion of naive T cells, Decreased total B cell count, Decreased total lymphocyte count, Desquamation of skin soon after birth, Diarrhea, Dry skin, Edema, Erythroderma, Failure to thrive, Fever, Hepatomegaly, Hypoplasia of the thymus, Hypoproteinemia, Hypothyroidism, Increased circulating IgG concentration, Increased total eosinophil count, Increased total leukocyte count, Jaundice, Lymphadenopathy, Lymph node hypoplasia, Lymphoma, Lymphoproliferative disorder, Nephrotic syndrome, obsolete Decreased proportion of CD4-positive helper T cells, obsolete Hypotrichosis, Otitis media, Pneumonia, Pruritus, Recurrent bacterial infections, Recurrent bacterial meningitis, Recurrent bacterial skin infections, Recurrent bronchitis, Recurrent cutaneous fungal infections, Recurrent fever, Recurrent fungal infections, Recurrent Haemophilus influenzae infections, Recurrent herpes, Recurrent opportunistic infections, Recurrent viral infections, Reduced total natural killer cell count, Sepsis, Severe B lymphocytopenia, Severe combined immunodeficiency, Severe recurrent varicella, Short toe, Sinusitis, Skin rash, Splenomegaly, Thickened skin, Thrombocytopenia, Thyroiditis

abnormal gut-associated lymphoid tissue morphology, abnormal hematopoietic system morphology/development, abnormal immune system organ morphology, abnormal maternal decidual layer morphology, abnormal mesenteric lymph node morphology, abnormal myelopoiesis, abnormal placenta metrial gland morphology, abnormal proerythroblast morphology, abnormal splenic cell ratio, abnormal thymocyte activation, absent gamma-delta intraepithelial T cell, absent gamma-delta T cells, absent Peyer's patches, absent spleen germinal center, absent spleen white pulp, absent uterine NK cells, arrested B cell differentiation, cecum inflammation, decreased CD4-positive, alpha beta T cell number, decreased double-negative T cell number, decreased double-positive T cell number, decreased IgG3 level, decreased immature B cell number, decreased interferon-gamma secretion, decreased interleukin-2 secretion, decreased interleukin-4 secretion, decreased mature B cell number, decreased myeloid dendritic cell number, decreased NK T cell number, decreased plasma cell number, decreased pre-B cell number, decreased regulatory T cell number, decreased single-positive T cell number, decreased spleen white pulp amount, decreased T cell proliferation, decreased thymocyte number, enlarged Peyer's patches, impaired natural killer cell mediated cytotoxicity, increased macrophage cell number, increased neutrophil cell number, no abnormal phenotype detected, prolonged diestrus, prolonged estrous cycle, prolonged metestrus, reproductive system phenotype, small lymph nodes, small thymus, small thymus cortex, spleen hyperplasia, thymus cortex hypoplasia