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Summary Expression Phenotypes Gene Literature (208) GO Terms (68) Nucleotides (135) Proteins (46) Interactants (1776) Wiki
XB-GENEPAGE-482481

lhx1     LIM homeobox 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal gastrulation (3 sources), abnormal head morphology (2 sources), abnormal tail morphology (2 sources), abnormal embryo morphology (1 source), abnormal tail bud morphology (1 source), abnormal ventral trunk morphology (1 source), abnormally delayed closure of blastopore (1 source), decreased length of anterior-posterior axis (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: lhx1 manipulated (5 sources), lhx1 assayed (13 sources)
Computed annotations: lhx1 assayed (34 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + lhx1 MO + otx2 MO (2 sources), Xtr Wt + lhx1 MO (2 sources), Xla Wt + lhx1 + otx2 (1 source), Xla Wt + lhx1 + otx2 + sia1 MO + sia2 MO (1 source), Xla Wt + lhx1 MO (1 source), Xla Wt + lhx1 MO (1 source), Xla Wt + lhx1 MO + otx2 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (62 sources): Mullerian duct degeneration, Wolffian duct degeneration, abnormal Mullerian duct morphology, abnormal Wolffian duct morphology, abnormal allantois morphology, abnormal anterior head development, abnormal brain development, abnormal egg cylinder morphology, abnormal endoderm development, abnormal female reproductive system morphology, [+]