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Summary Expression Phenotypes Gene Literature (486) GO Terms (9) Nucleotides (58) Proteins (31) Interactants (1532) Wiki

nodal     nodal growth differentiation factor

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased length of anterior-posterior axis (4 sources), abnormal head morphology (3 sources), wholly dorsalized embryo (3 sources), abnormal gastrulation (2 sources), abnormal axis elongation (1 source), abnormal proctodeum morphology (1 source), abnormal tadpole morphology (1 source), abnormal tail bud morphology (1 source), abnormal tail morphology (1 source), abnormal ventral trunk morphology (1 source), abnormally delayed closure of blastopore (1 source), absent head (1 source), absent tail (1 source), decreased length of tail (1 source), decreased size of the whole organism (1 source), tail abnormally curved dorsally (1 source), wholly ventralized embryo (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: nodal assayed (11 sources)
Computed annotations: nodal assayed (9 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + nodal1 MO (2 sources), Xtr Wt + nodal3.1 MO (2 sources), Xla Wt + nodal (1 source), Xla Wt + nodal1 (1 source), Xla Wt + nodal1 (1 source), Xla Wt + nodal1 + animal cap explant (1 source), Xla Wt + nodal1 + ctnnb1 MO (1 source), Xla Wt + nodal1 + sia1 MO + sia2 MO (1 source), Xla Wt + nodal1 + tle4 (1 source), Xla Wt + nodal1 + dntcf3 (1 source), Xla Wt + nodal2 (1 source), Xla Wt + nodal2 + animal cap explant (1 source), Xla Wt + nodal2 + animal cap explant (1 source), Xla Wt + nodal5 (1 source), Xla Wt + wnt8a + nodal2 + animal cap explant (1 source), Xtr Wt + nodal3.1 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (41 sources): Abdominal situs inversus, Abnormality of cardiovascular system morphology, Abnormality of the respiratory system, Agenesis of corpus callosum, Ambiguous genitalia, Anteverted nares, Asthma, Atrial septal defect, Choanal atresia, Cleft palate, [+]
Mouse (96 sources): abnormal anterior visceral endoderm morphology, abnormal brain development, abnormal craniofacial development, abnormal developmental patterning, abnormal digestive system development, abnormal direction of heart looping, abnormal distal visceral endoderm morphology, abnormal ectoderm development, abnormal embryo turning, abnormal embryonic neuroepithelium morphology, [+]

View all ortholog results at Monarch