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XB-GENEPAGE-483208
nodal nodal growth differentiation factor
Anatomical Phenotypes
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decreased length of anterior-posterior axis (4 sources), abnormal head morphology (3 sources), wholly dorsalized embryo (3 sources), abnormal gastrulation (2 sources), abnormal axis elongation (1 source), abnormal proctodeum morphology (1 source), abnormal tadpole morphology (1 source), abnormal tail bud morphology (1 source), abnormal tail morphology (1 source), abnormal ventral trunk morphology (1 source), abnormally delayed closure of blastopore (1 source), absent head (1 source), absent tail (1 source), decreased length of tail (1 source), decreased size of the whole organism (1 source), tail abnormally curved dorsally (1 source), wholly ventralized embryo (1 source) |
Expression Phenotypes
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Manual annotations: nodal assayed (11 sources) |
Computed annotations: nodal assayed (9 sources) |
Experiments (Reagents)
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Xtr Wt + nodal1 MO (2 sources), Xtr Wt + nodal3.1 MO (2 sources), Xla Wt + nodal (1 source), Xla Wt + nodal1 (1 source), Xla Wt + nodal1 (1 source), Xla Wt + nodal1 + animal cap explant (1 source), Xla Wt + nodal1 + ctnnb1 MO (1 source), Xla Wt + nodal1 + sia1 MO + sia2 MO (1 source), Xla Wt + nodal1 + tle4 (1 source), Xla Wt + nodal1 + dntcf3 (1 source), Xla Wt + nodal2 (1 source), Xla Wt + nodal2 + animal cap explant (1 source), Xla Wt + nodal2 + animal cap explant (1 source), Xla Wt + nodal5 (1 source), Xla Wt + wnt8a + nodal2 + animal cap explant (1 source), Xtr Wt + nodal3.1 MO (1 source) |
Monarch Ortholog Phenotypes
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Human (41 sources): Abdominal situs inversus, Abnormality of cardiovascular system morphology, Abnormality of the respiratory system, Agenesis of corpus callosum, Ambiguous genitalia, Anteverted nares, Asthma, Atrial septal defect, Choanal atresia, Cleft palate, [+] |
Mouse (96 sources): abnormal anterior visceral endoderm morphology, abnormal brain development, abnormal craniofacial development, abnormal developmental patterning, abnormal digestive system development, abnormal direction of heart looping, abnormal distal visceral endoderm morphology, abnormal ectoderm development, abnormal embryo turning, abnormal embryonic neuroepithelium morphology, [+] |
View all ortholog results at Monarch |