tank Phenotypes

XB-GENEPAGE-483296

Gene Symbol: tank Gene Name: TRAF family member associated NFKB activator

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tank assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (17 sources): abnormal dendritic cell physiology, abnormal macrophage physiology, abnormal plasmacytoid dendritic cell physiology, increased B cell proliferation, increased IgG1 level, increased IgG2a level, increased IgG2b level, increased anti-double stranded DNA antibody level, increased anti-nuclear antigen antibody level, increased interferon-alpha secretion, increased interleukin-6 secretion, increased mature B cell number, increased plasma cell number, increased tumor necrosis factor secretion, premature death, renal glomerular immunoglobulin deposits, spleen hyperplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (17 sources): abnormal dendritic cell physiology, abnormal macrophage physiology, abnormal plasmacytoid dendritic cell physiology, increased B cell proliferation, increased IgG1 level, increased IgG2a level, increased IgG2b level, increased anti-double stranded DNA antibody level, increased anti-nuclear antigen antibody level, increased interferon-alpha secretion, [+]