abnormal cartilage development, abnormal cerebellum development, abnormal circulating mineral level, abnormal conotruncal ridge morphology, abnormal craniofacial bone morphology, abnormal exocrine pancreas morphology, abnormal kidney collecting duct morphology, abnormal kidney epithelial cell primary cilium physiology, abnormal kidney epithelium morphology, abnormal kidney morphology, abnormal mitotic spindle morphology, abnormal myocardium layer morphology, abnormal osteoblast differentiation, abnormal pancreatic acinus morphology, abnormal perichondrium morphology, abnormal peroxisome morphology, abnormal placenta development, abnormal placenta morphology, abnormal placenta vasculature, abnormal presphenoid synchondrosis, abnormal renal glomerulus morphology, abnormal renal tubule epithelium morphology, abnormal sagittal suture morphology, abnormal skeleton development, abnormal sphenoid bone morphology, abnormal sphenooccipital synchondrosis, abnormal spine curvature, abnormal thyroid cartilage morphology, cardiac fibrosis, cardiac hypertrophy, cardiovascular system phenotype, chondrodystrophy, common atrioventricular valve, decreased body size, decreased bone mineralization, decreased chondrocyte proliferation, decreased circulating alkaline phosphatase level, decreased circulating glucose level, decreased compact bone mass, decreased embryo size, decreased fatty acid oxidation, decreased hematocrit, decreased pancreatic islet number, decreased trabecular bone mass, decreased trabecular bone volume, decreased urine creatinine level, decreased urine osmolality, decreased urine protein level, decreased urine urea nitrogen level, decreased width of hypertrophic chondrocyte zone, delayed bone ossification, delayed endochondral bone ossification, delayed intramembranous bone ossification, dilated bile duct, dilated heart, dilated pancreatic duct, dilated proximal convoluted tubule, dilated renal tubules, disproportionate dwarf, dissociated hepatocytes, domed cranium, dystrophic cardiac calcinosis, embryonic lethality during organogenesis, embryonic lethality during organogenesis, incomplete penetrance, endocrine/exocrine gland phenotype, enlarged pancreas, exocrine pancreas atrophy, failure of atrioventricular cushion closure, hematopoietic system phenotype, homeostasis/metabolism phenotype, impaired osteoblast differentiation, increased blood osmolality, increased cardiac muscle contractility, increased cardiac output, increased cardiac stroke volume, increased cell proliferation, increased circulating creatinine level, increased circulating parathyroid hormone level, increased heart weight, increased hepatocyte proliferation, increased kidney apoptosis, increased kidney cell proliferation, increased kidney epithelial cell primary cilium length, increased kidney weight, increased osteoblast proliferation, increased renal tubule apoptosis, increased urine osmolality, kidney epithelium hyperplasia, kidney medulla cyst, lethality throughout fetal growth and development, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, lethality, complete penetrance, liver/biliary system phenotype, neonatal lethality, complete penetrance, no abnormal phenotype detected, oxidative stress, pale kidney, pancreas lipomatosis, perinatal lethality, complete penetrance, perinatal lethality, incomplete penetrance, postnatal lethality, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature cranial synchondrosis closure, premature death, premature presphenoid synchondrosis closure, premature sphenooccipital synchondrosis closure, prenatal lethality, complete penetrance, prenatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, renal cast, renal glomerulus cyst, renal/urinary system phenotype, respiratory system phenotype, short frontal bone, short mandible, short maxilla, short premaxilla, short presphenoid bone, skin edema, slow postnatal weight gain, small cerebellum, small lung, subarachnoid hemorrhage, thick interventricular septum, thick myocardium, thick ventricular wall, thin myocardium